iPSC-sEVs alleviate microglia senescence to protect against ischemic stroke in aged mice

The polarization of microglia plays an important role in the outcome of ischemic stroke (IS). In the aged population, senescent microglia show a predominant pro-inflammatory phenotype, which leads to worse outcomes in aged ischemic stroke compared to young ischemic stroke. Recent research demonstrat...

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Detalles Bibliográficos
Autores principales: Niu, Xinyu, Xia, Yuguo, Luo, Lei, Chen, Yu, Yuan, Ji, Zhang, Juntao, Zheng, Xianyou, Li, Qing, Deng, Zhifeng, Wang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020681/
https://www.ncbi.nlm.nih.gov/pubmed/36936398
http://dx.doi.org/10.1016/j.mtbio.2023.100600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020681/
https://www.ncbi.nlm.nih.gov/pubmed/36936398
http://dx.doi.org/10.1016/j.mtbio.2023.100600

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