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Emodin ameliorates renal injury and fibrosis via regulating the miR-490-3p/HMGA2 axis

Renal fibrosis is a major pathological feature of chronic kidney disease (CKD). While emodin is reported to elicit anti-fibrotic effects on renal injury, little is known about its effects on microRNA (miRNA)-modulated mechanisms in renal fibrosis. In this study, we established a unilateral ureteral...

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Detalles Bibliográficos
Autores principales: Wang, Liulin, Wang, Xuerui, Li, Gang, Zhou, Shanshan, Wang, Rui, Long, Qi, Wang, Min, Li, Liang, Huang, Hai, Ba, Yuanming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020706/
https://www.ncbi.nlm.nih.gov/pubmed/36937888
http://dx.doi.org/10.3389/fphar.2023.1042093