A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma

PURPOSE: To demonstrate novel treatments for patients with high juvenile xanthogranuloma (JXG) eyelid lesion burden. CASE REPORT: A 14-year-old girl was referred to the oculoplastic surgery service for management of worsening extensive bilateral eyelid and adnexal lesions in the setting of JXG. The...

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Detalles Bibliográficos
Autores principales: Van Brummen, Alexandra, Jacobs, Sarah, Feng, Shu, Li, Emily, J. Amadi, Arash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PUBLISHED BY KNOWLEDGE E 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020784/
https://www.ncbi.nlm.nih.gov/pubmed/36937193
http://dx.doi.org/10.18502/jovr.v18i1.12733
Descripción
Sumario:PURPOSE: To demonstrate novel treatments for patients with high juvenile xanthogranuloma (JXG) eyelid lesion burden. CASE REPORT: A 14-year-old girl was referred to the oculoplastic surgery service for management of worsening extensive bilateral eyelid and adnexal lesions in the setting of JXG. The patient underwent intra-lesional steroid injections, serial excisions, and reconstruction with skin grafts. She was subsequently treated with CO [Formula: see text] laser-assisted topical steroid application, which resulted in lesion regression. CONCLUSION: A novel multimodal approach to treatment of severe periocular JXG, incorporating surgical debulking, skin autograft, CO2 laser, and intra-lesional steroids, can be effective for lesion control.

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