A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma

PURPOSE: To demonstrate novel treatments for patients with high juvenile xanthogranuloma (JXG) eyelid lesion burden. CASE REPORT: A 14-year-old girl was referred to the oculoplastic surgery service for management of worsening extensive bilateral eyelid and adnexal lesions in the setting of JXG. The...

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Autores principales: Van Brummen, Alexandra, Jacobs, Sarah, Feng, Shu, Li, Emily, J. Amadi, Arash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PUBLISHED BY KNOWLEDGE E 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020784/
https://www.ncbi.nlm.nih.gov/pubmed/36937193
http://dx.doi.org/10.18502/jovr.v18i1.12733
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author Van Brummen, Alexandra
Jacobs, Sarah
Feng, Shu
Li, Emily
J. Amadi, Arash
author_facet Van Brummen, Alexandra
Jacobs, Sarah
Feng, Shu
Li, Emily
J. Amadi, Arash
author_sort Van Brummen, Alexandra
collection PubMed
description PURPOSE: To demonstrate novel treatments for patients with high juvenile xanthogranuloma (JXG) eyelid lesion burden. CASE REPORT: A 14-year-old girl was referred to the oculoplastic surgery service for management of worsening extensive bilateral eyelid and adnexal lesions in the setting of JXG. The patient underwent intra-lesional steroid injections, serial excisions, and reconstruction with skin grafts. She was subsequently treated with CO [Formula: see text] laser-assisted topical steroid application, which resulted in lesion regression. CONCLUSION: A novel multimodal approach to treatment of severe periocular JXG, incorporating surgical debulking, skin autograft, CO2 laser, and intra-lesional steroids, can be effective for lesion control.
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spelling pubmed-100207842023-03-18 A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma Van Brummen, Alexandra Jacobs, Sarah Feng, Shu Li, Emily J. Amadi, Arash J Ophthalmic Vis Res Case Report PURPOSE: To demonstrate novel treatments for patients with high juvenile xanthogranuloma (JXG) eyelid lesion burden. CASE REPORT: A 14-year-old girl was referred to the oculoplastic surgery service for management of worsening extensive bilateral eyelid and adnexal lesions in the setting of JXG. The patient underwent intra-lesional steroid injections, serial excisions, and reconstruction with skin grafts. She was subsequently treated with CO [Formula: see text] laser-assisted topical steroid application, which resulted in lesion regression. CONCLUSION: A novel multimodal approach to treatment of severe periocular JXG, incorporating surgical debulking, skin autograft, CO2 laser, and intra-lesional steroids, can be effective for lesion control. PUBLISHED BY KNOWLEDGE E 2023-02-21 /pmc/articles/PMC10020784/ /pubmed/36937193 http://dx.doi.org/10.18502/jovr.v18i1.12733 Text en Copyright © 2023 Van Brummen et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Van Brummen, Alexandra
Jacobs, Sarah
Feng, Shu
Li, Emily
J. Amadi, Arash
A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma
title A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma
title_full A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma
title_fullStr A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma
title_full_unstemmed A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma
title_short A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma
title_sort multifaceted approach to treatment of recalcitrant cutaneous periorbital juvenile xanthogranuloma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020784/
https://www.ncbi.nlm.nih.gov/pubmed/36937193
http://dx.doi.org/10.18502/jovr.v18i1.12733
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