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Phase II Trials of Iniparib (BSI-201) in Combination with Gemcitabine and Carboplatin in Patients with Recurrent Ovarian Cancer

BACKGROUND: Iniparib (BSI-201), a novel anticancer agent thought to have poly(ADP-ribose) polymerase (PARP) inhibitory activity and synergy with both gemcitabine and carboplatin (GC) was evaluated in 2 cohorts with GC. METHODS: Parallel multicenter, single-arm, phase II studies using a Simon two-sta...

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Detalles Bibliográficos
Autores principales:	Penson, Richard T, Ambrosio, Allison J, Whalen, Christin A, Krasner, Carolyn N, Konstantinopoulos, Panagiotis A, Bradley, Charles, Matulonis, Ursula A, Birrer, Michael J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Gynecologic Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020803/ https://www.ncbi.nlm.nih.gov/pubmed/36718018 http://dx.doi.org/10.1093/oncolo/oyac275

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