In vivo loss of tumorigenicity in a patient-derived orthotopic xenograft mouse model of ependymoma

INTRODUCTION: Ependymomas (EPN) are the third most common malignant brain cancer in children. Treatment strategies for pediatric EPN have remained unchanged over recent decades, with 10-year survival rates stagnating at just 67% for children aged 0-14 years. Moreover, a proportion of patients who su...

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Detalles Bibliográficos
Autores principales: Whitehouse, Jacqueline P., Hii, Hilary, Mayoh, Chelsea, Wong, Marie, Ajuyah, Pamela, Barahona, Paulette, Cui, Louise, Dholaria, Hetal, White, Christine L., Buntine, Molly K., Byrne, Jacob, Rodrigues da Silva, Keteryne, Howlett, Meegan, Girard, Emily J., Tsoli, Maria, Ziegler, David S., Dyke, Jason M., Lee, Sharon, Ekert, Paul G., Cowley, Mark J., Gottardo, Nicholas G., Endersby, Raelene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020925/
https://www.ncbi.nlm.nih.gov/pubmed/36937401
http://dx.doi.org/10.3389/fonc.2023.1123492

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