2-(4-Fluorophenyl)-1H-benzo[d]imidazole as a Promising Template for the Development of Metabolically Robust, α1β2γ2GABA-A Receptor-Positive Allosteric Modulators

[Image: see text] Modulation of α1β2γ2GABA-A receptor subpopulation expressed in the basal ganglia region is a conceptually novel mode of pharmacological strategy that offers prospects to tackle a variety of neurological dysfunction. Although clinical findings provided compelling evidence for the va...

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Detalles Bibliográficos
Autores principales: Marcinkowska, Monika, Fajkis-Zajączkowska, Nikola, Szafrańska, Katarzyna, Jończyk, Jakub, Siwek, Agata, Mordyl, Barbara, Karcz, Tadeusz, Latacz, Gniewomir, Kolaczkowski, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020958/
https://www.ncbi.nlm.nih.gov/pubmed/36848624
http://dx.doi.org/10.1021/acschemneuro.2c00800

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