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Enhancing Protein Crystal Nucleation Using In Situ Templating on Bioconjugate-Functionalized Nanoparticles and Machine Learning

[Image: see text] Although protein crystallization offers a promising alternative to chromatography for lower-cost protein purification, slow nucleation kinetics and high protein concentration requirements are major barriers for using crystallization as a viable strategy in downstream protein purifi...

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Detalles Bibliográficos
Autores principales: McCue, Caroline, Girard, Henri-Louis, Varanasi, Kripa K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020963/
https://www.ncbi.nlm.nih.gov/pubmed/36853011
http://dx.doi.org/10.1021/acsami.2c17208