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HSC Niche Dynamics in Regeneration, Pre-malignancy, and Cancer: Insights From Mathematical Modeling

The hematopoietic stem cell (HSC) niche is a crucial driver of regeneration and malignancy. Its interaction with hematopoietic and malignant stem cells is highly complex and direct experimental observations are challenging. We here develop a mathematical model which helps relate processes in the nic...

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Detalles Bibliográficos
Autores principales:	Pedersen, Rasmus Kristoffer, Andersen, Morten, Skov, Vibe, Kjær, Lasse, Hasselbalch, Hans C, Ottesen, Johnny T, Stiehl, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Cancer Stem Cells
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020982/ https://www.ncbi.nlm.nih.gov/pubmed/36371719 http://dx.doi.org/10.1093/stmcls/sxac079

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