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Real-Time Pyruvate Chemical Conversion Monitoring Enabled by PHIP
[Image: see text] In recent years, parahydrogen-induced polarization side arm hydrogenation (PHIP-SAH) has been applied to hyperpolarize [1-(13)C]pyruvate and map its metabolic conversion to [1-(13)C]lactate in cancer cells. Developing on our recent MINERVA pulse sequence protocol, in which we have...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021011/ https://www.ncbi.nlm.nih.gov/pubmed/36857108 http://dx.doi.org/10.1021/jacs.2c13198 |