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Real-Time Pyruvate Chemical Conversion Monitoring Enabled by PHIP

[Image: see text] In recent years, parahydrogen-induced polarization side arm hydrogenation (PHIP-SAH) has been applied to hyperpolarize [1-(13)C]pyruvate and map its metabolic conversion to [1-(13)C]lactate in cancer cells. Developing on our recent MINERVA pulse sequence protocol, in which we have...

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Detalles Bibliográficos
Autores principales: Stevanato, Gabriele, Ding, Yonghong, Mamone, Salvatore, Jagtap, Anil P., Korchak, Sergey, Glöggler, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021011/
https://www.ncbi.nlm.nih.gov/pubmed/36857108
http://dx.doi.org/10.1021/jacs.2c13198