Novel multivalent S100A8 inhibitory peptides attenuate tumor progression and metastasis by inhibiting the TLR4-dependent pathway

The tumor-elicited inflammation is closely related to tumor microenvironment during tumor progression. S100A8, an endogenous ligand of Toll-like receptor 4 (TLR4), is known as a key molecule in the tumor microenvironment and premetastatic niche formation. We firstly generated a novel multivalent S10...

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Detalles Bibliográficos
Autores principales: Deguchi, Atsuko, Watanabe-Takahashi, Miho, Mishima, Taishi, Omori, Tsutomu, Ohto, Umeharu, Arashiki, Nobuto, Nakamura, Fumio, Nishikawa, Kiyotaka, Maru, Yoshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021052/
https://www.ncbi.nlm.nih.gov/pubmed/36932197
http://dx.doi.org/10.1038/s41417-023-00604-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021052/
https://www.ncbi.nlm.nih.gov/pubmed/36932197
http://dx.doi.org/10.1038/s41417-023-00604-3

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