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Stem Cells: Recent Developments Redefining Epilepsy Therapy

The field of stem cell therapy is growing rapidly and hopes to offer an alternative solution to diseases that are historically treated medically or surgically. One such focus of research is the treatment of medically refractory epilepsy, which is traditionally approached from a surgical or intervent...

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Autores principales: Alayli, Adam, Lockard, Gavin, Gordon, Jonah, Connolly, Jacob, Monsour, Molly, Schimmel, Samantha, Dela Peña, Ike, Borlongan, Cesar V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021095/
https://www.ncbi.nlm.nih.gov/pubmed/36919673
http://dx.doi.org/10.1177/09636897231158967
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author Alayli, Adam
Lockard, Gavin
Gordon, Jonah
Connolly, Jacob
Monsour, Molly
Schimmel, Samantha
Dela Peña, Ike
Borlongan, Cesar V.
author_facet Alayli, Adam
Lockard, Gavin
Gordon, Jonah
Connolly, Jacob
Monsour, Molly
Schimmel, Samantha
Dela Peña, Ike
Borlongan, Cesar V.
author_sort Alayli, Adam
collection PubMed
description The field of stem cell therapy is growing rapidly and hopes to offer an alternative solution to diseases that are historically treated medically or surgically. One such focus of research is the treatment of medically refractory epilepsy, which is traditionally approached from a surgical or interventional standpoint. Research shows that stem cell transplantation has potential to offer significant benefits to the epilepsy patient by reducing seizure frequency, intensity, and neurological deficits that often result from the condition. This review explores the basic science progress made on the topic of stem cells and epilepsy by focusing on experiments using animal models and highlighting the most recent developments from the last 4 years.
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spelling pubmed-100210952023-03-18 Stem Cells: Recent Developments Redefining Epilepsy Therapy Alayli, Adam Lockard, Gavin Gordon, Jonah Connolly, Jacob Monsour, Molly Schimmel, Samantha Dela Peña, Ike Borlongan, Cesar V. Cell Transplant Review The field of stem cell therapy is growing rapidly and hopes to offer an alternative solution to diseases that are historically treated medically or surgically. One such focus of research is the treatment of medically refractory epilepsy, which is traditionally approached from a surgical or interventional standpoint. Research shows that stem cell transplantation has potential to offer significant benefits to the epilepsy patient by reducing seizure frequency, intensity, and neurological deficits that often result from the condition. This review explores the basic science progress made on the topic of stem cells and epilepsy by focusing on experiments using animal models and highlighting the most recent developments from the last 4 years. SAGE Publications 2023-03-15 /pmc/articles/PMC10021095/ /pubmed/36919673 http://dx.doi.org/10.1177/09636897231158967 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review
Alayli, Adam
Lockard, Gavin
Gordon, Jonah
Connolly, Jacob
Monsour, Molly
Schimmel, Samantha
Dela Peña, Ike
Borlongan, Cesar V.
Stem Cells: Recent Developments Redefining Epilepsy Therapy
title Stem Cells: Recent Developments Redefining Epilepsy Therapy
title_full Stem Cells: Recent Developments Redefining Epilepsy Therapy
title_fullStr Stem Cells: Recent Developments Redefining Epilepsy Therapy
title_full_unstemmed Stem Cells: Recent Developments Redefining Epilepsy Therapy
title_short Stem Cells: Recent Developments Redefining Epilepsy Therapy
title_sort stem cells: recent developments redefining epilepsy therapy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021095/
https://www.ncbi.nlm.nih.gov/pubmed/36919673
http://dx.doi.org/10.1177/09636897231158967
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