Cargando…

Global trends in antimicrobial use in food-producing animals: 2020 to 2030

Use of antimicrobials in farming has enabled the growth of intensive animal production and helped in meeting the global increase in demand for animal protein. However, the widespread use of veterinary antimicrobials drives antimicrobial resistance, with important consequences for animal health, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Mulchandani, Ranya, Wang, Yu, Gilbert, Marius, Van Boeckel, Thomas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021213/
https://www.ncbi.nlm.nih.gov/pubmed/36963007
http://dx.doi.org/10.1371/journal.pgph.0001305
_version_ 1784908429345685504
author Mulchandani, Ranya
Wang, Yu
Gilbert, Marius
Van Boeckel, Thomas P.
author_facet Mulchandani, Ranya
Wang, Yu
Gilbert, Marius
Van Boeckel, Thomas P.
author_sort Mulchandani, Ranya
collection PubMed
description Use of antimicrobials in farming has enabled the growth of intensive animal production and helped in meeting the global increase in demand for animal protein. However, the widespread use of veterinary antimicrobials drives antimicrobial resistance, with important consequences for animal health, and potentially human health. Global monitoring of antimicrobial use is essential: first, to track progress in reducing the reliance of farming on antimicrobials. Second, to identify countries where antimicrobial-stewardship efforts should be targeted to curb antimicrobial resistance. Data on usage of antimicrobials in food animals were collected from 42 countries. Multivariate regression models were used in combination with projections of animal counts for cattle, sheep, chicken, and pigs from the Food and Agriculture Organization to estimate global antimicrobial usage of veterinary antimicrobials in 2020 and 2030. Maps of animal densities were used to identify geographic hotspots of antimicrobial use. In each country, estimates of antimicrobial use (tonnes) were calibrated to match continental-level reports of antimicrobial use intensity (milligrams per kilogram of animal) from the World Organization for Animal Health, as well as country-level reports of antimicrobial use from countries that made this information publicly available. Globally, antimicrobial usage was estimated at 99,502 tonnes (95% CI 68,535–198,052) in 2020 and is projected, based on current trends, to increase by 8.0% to 107,472 tonnes (95% CI: 75,927–202,661) by 2030. Hotspots of antimicrobial use were overwhelmingly in Asia (67%), while <1% were in Africa. Findings indicate higher global antimicrobial usage in 2030 compared to prior projections that used data from 2017; this is likely associated with an upward revision of antimicrobial use in Asia/Oceania (~6,000 tonnes) and the Americas (~4,000 tonnes). National-level reporting of antimicrobial use should be encouraged to better evaluate the impact of national policies on antimicrobial use levels.
format Online
Article
Text
id pubmed-10021213
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-100212132023-03-17 Global trends in antimicrobial use in food-producing animals: 2020 to 2030 Mulchandani, Ranya Wang, Yu Gilbert, Marius Van Boeckel, Thomas P. PLOS Glob Public Health Research Article Use of antimicrobials in farming has enabled the growth of intensive animal production and helped in meeting the global increase in demand for animal protein. However, the widespread use of veterinary antimicrobials drives antimicrobial resistance, with important consequences for animal health, and potentially human health. Global monitoring of antimicrobial use is essential: first, to track progress in reducing the reliance of farming on antimicrobials. Second, to identify countries where antimicrobial-stewardship efforts should be targeted to curb antimicrobial resistance. Data on usage of antimicrobials in food animals were collected from 42 countries. Multivariate regression models were used in combination with projections of animal counts for cattle, sheep, chicken, and pigs from the Food and Agriculture Organization to estimate global antimicrobial usage of veterinary antimicrobials in 2020 and 2030. Maps of animal densities were used to identify geographic hotspots of antimicrobial use. In each country, estimates of antimicrobial use (tonnes) were calibrated to match continental-level reports of antimicrobial use intensity (milligrams per kilogram of animal) from the World Organization for Animal Health, as well as country-level reports of antimicrobial use from countries that made this information publicly available. Globally, antimicrobial usage was estimated at 99,502 tonnes (95% CI 68,535–198,052) in 2020 and is projected, based on current trends, to increase by 8.0% to 107,472 tonnes (95% CI: 75,927–202,661) by 2030. Hotspots of antimicrobial use were overwhelmingly in Asia (67%), while <1% were in Africa. Findings indicate higher global antimicrobial usage in 2030 compared to prior projections that used data from 2017; this is likely associated with an upward revision of antimicrobial use in Asia/Oceania (~6,000 tonnes) and the Americas (~4,000 tonnes). National-level reporting of antimicrobial use should be encouraged to better evaluate the impact of national policies on antimicrobial use levels. Public Library of Science 2023-02-01 /pmc/articles/PMC10021213/ /pubmed/36963007 http://dx.doi.org/10.1371/journal.pgph.0001305 Text en © 2023 Mulchandani et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Mulchandani, Ranya
Wang, Yu
Gilbert, Marius
Van Boeckel, Thomas P.
Global trends in antimicrobial use in food-producing animals: 2020 to 2030
title Global trends in antimicrobial use in food-producing animals: 2020 to 2030
title_full Global trends in antimicrobial use in food-producing animals: 2020 to 2030
title_fullStr Global trends in antimicrobial use in food-producing animals: 2020 to 2030
title_full_unstemmed Global trends in antimicrobial use in food-producing animals: 2020 to 2030
title_short Global trends in antimicrobial use in food-producing animals: 2020 to 2030
title_sort global trends in antimicrobial use in food-producing animals: 2020 to 2030
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021213/
https://www.ncbi.nlm.nih.gov/pubmed/36963007
http://dx.doi.org/10.1371/journal.pgph.0001305
work_keys_str_mv AT mulchandaniranya globaltrendsinantimicrobialuseinfoodproducinganimals2020to2030
AT wangyu globaltrendsinantimicrobialuseinfoodproducinganimals2020to2030
AT gilbertmarius globaltrendsinantimicrobialuseinfoodproducinganimals2020to2030
AT vanboeckelthomasp globaltrendsinantimicrobialuseinfoodproducinganimals2020to2030