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Critical weaknesses in shielding strategies for COVID-19
The COVID-19 pandemic, caused by the coronavirus SARS-CoV-2, has led to a wide range of non-pharmaceutical interventions being implemented around the world to curb transmission. However, the economic and social costs of some of these measures, especially lockdowns, has been high. An alternative and...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021285/ https://www.ncbi.nlm.nih.gov/pubmed/36962415 http://dx.doi.org/10.1371/journal.pgph.0000298 |
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author | Smith, Cameron A. Yates, Christian A. Ashby, Ben |
author_facet | Smith, Cameron A. Yates, Christian A. Ashby, Ben |
author_sort | Smith, Cameron A. |
collection | PubMed |
description | The COVID-19 pandemic, caused by the coronavirus SARS-CoV-2, has led to a wide range of non-pharmaceutical interventions being implemented around the world to curb transmission. However, the economic and social costs of some of these measures, especially lockdowns, has been high. An alternative and widely discussed public health strategy for the COVID-19 pandemic would have been to ‘shield’ those most vulnerable to COVID-19 (minimising their contacts with others), while allowing infection to spread among lower risk individuals with the aim of reaching herd immunity. Here we retrospectively explore the effectiveness of this strategy using a stochastic SEIR framework, showing that even under the unrealistic assumption of perfect shielding, hospitals would have been rapidly overwhelmed with many avoidable deaths among lower risk individuals. Crucially, even a small (20%) reduction in the effectiveness of shielding would have likely led to a large increase (>150%) in the number of deaths compared to perfect shielding. Our findings demonstrate that shielding the vulnerable while allowing infections to spread among the wider population would not have been a viable public health strategy for COVID-19 and is unlikely to be effective for future pandemics. |
format | Online Article Text |
id | pubmed-10021285 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-100212852023-03-17 Critical weaknesses in shielding strategies for COVID-19 Smith, Cameron A. Yates, Christian A. Ashby, Ben PLOS Glob Public Health Research Article The COVID-19 pandemic, caused by the coronavirus SARS-CoV-2, has led to a wide range of non-pharmaceutical interventions being implemented around the world to curb transmission. However, the economic and social costs of some of these measures, especially lockdowns, has been high. An alternative and widely discussed public health strategy for the COVID-19 pandemic would have been to ‘shield’ those most vulnerable to COVID-19 (minimising their contacts with others), while allowing infection to spread among lower risk individuals with the aim of reaching herd immunity. Here we retrospectively explore the effectiveness of this strategy using a stochastic SEIR framework, showing that even under the unrealistic assumption of perfect shielding, hospitals would have been rapidly overwhelmed with many avoidable deaths among lower risk individuals. Crucially, even a small (20%) reduction in the effectiveness of shielding would have likely led to a large increase (>150%) in the number of deaths compared to perfect shielding. Our findings demonstrate that shielding the vulnerable while allowing infections to spread among the wider population would not have been a viable public health strategy for COVID-19 and is unlikely to be effective for future pandemics. Public Library of Science 2022-04-26 /pmc/articles/PMC10021285/ /pubmed/36962415 http://dx.doi.org/10.1371/journal.pgph.0000298 Text en © 2022 Smith et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Smith, Cameron A. Yates, Christian A. Ashby, Ben Critical weaknesses in shielding strategies for COVID-19 |
title | Critical weaknesses in shielding strategies for COVID-19 |
title_full | Critical weaknesses in shielding strategies for COVID-19 |
title_fullStr | Critical weaknesses in shielding strategies for COVID-19 |
title_full_unstemmed | Critical weaknesses in shielding strategies for COVID-19 |
title_short | Critical weaknesses in shielding strategies for COVID-19 |
title_sort | critical weaknesses in shielding strategies for covid-19 |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021285/ https://www.ncbi.nlm.nih.gov/pubmed/36962415 http://dx.doi.org/10.1371/journal.pgph.0000298 |
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