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Tap water as the source of a Legionnaires’ disease outbreak spread to several residential buildings and one hospital, Finland, 2020 to 2021

In Finland, all microbiology laboratories notify Legionella findings and physicians notify Legionnaires’ disease (LD) cases to the National Infectious Disease Register. All cases are interviewed, and water samples obtained from potential places of exposure. Legionella isolates from humans and water...

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Autores principales: Mentula, Silja, Kääriäinen, Sohvi, Jaakola, Sari, Niittynen, Marjo, Airaksinen, Piia, Koivula, Irma, Lehtola, Markku, Mauranen, Ella, Mononen, Isto, Savolainen, Raija, Haatainen, Susanna, Lyytikäinen, Outi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021472/
https://www.ncbi.nlm.nih.gov/pubmed/36927717
http://dx.doi.org/10.2807/1560-7917.ES.2023.28.11.2200673
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author Mentula, Silja
Kääriäinen, Sohvi
Jaakola, Sari
Niittynen, Marjo
Airaksinen, Piia
Koivula, Irma
Lehtola, Markku
Mauranen, Ella
Mononen, Isto
Savolainen, Raija
Haatainen, Susanna
Lyytikäinen, Outi
author_facet Mentula, Silja
Kääriäinen, Sohvi
Jaakola, Sari
Niittynen, Marjo
Airaksinen, Piia
Koivula, Irma
Lehtola, Markku
Mauranen, Ella
Mononen, Isto
Savolainen, Raija
Haatainen, Susanna
Lyytikäinen, Outi
author_sort Mentula, Silja
collection PubMed
description In Finland, all microbiology laboratories notify Legionella findings and physicians notify Legionnaires’ disease (LD) cases to the National Infectious Disease Register. All cases are interviewed, and water samples obtained from potential places of exposure. Legionella isolates from humans and water are compared by whole genome sequencing (WGS). In March 2021, Legionella pneumophila serogroup 1 (Lp 1) pneumonia cases increased in one Finnish city (120,000 inhabitants) where single LD cases are detected annually. We identified 12 LD cases, nine living in different residential buildings and three nosocomial, linked by identical human and/or water isolates. Three of these cases were from January 2020, October 2020 and February 2021 and identified retrospectively. Eleven were diagnosed by urinary antigen test, 10 by PCR and five by culture; age ranged between 52 and 85 years, and 10 had underlying diseases. Nine of 12 homes of LD cases and 15 of 26 water samples from the hospital were positive for Lp 1, with concentrations up to 640,000 cfu/L. Water samples from regional storage tanks were negative. Positivity in homes and the hospital suggested inadequate maintenance measures. Enhanced surveillance combined with WGS was crucial in detecting this unusual LD outbreak related to domestic and hospital water systems.
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spelling pubmed-100214722023-03-18 Tap water as the source of a Legionnaires’ disease outbreak spread to several residential buildings and one hospital, Finland, 2020 to 2021 Mentula, Silja Kääriäinen, Sohvi Jaakola, Sari Niittynen, Marjo Airaksinen, Piia Koivula, Irma Lehtola, Markku Mauranen, Ella Mononen, Isto Savolainen, Raija Haatainen, Susanna Lyytikäinen, Outi Euro Surveill Outbreaks In Finland, all microbiology laboratories notify Legionella findings and physicians notify Legionnaires’ disease (LD) cases to the National Infectious Disease Register. All cases are interviewed, and water samples obtained from potential places of exposure. Legionella isolates from humans and water are compared by whole genome sequencing (WGS). In March 2021, Legionella pneumophila serogroup 1 (Lp 1) pneumonia cases increased in one Finnish city (120,000 inhabitants) where single LD cases are detected annually. We identified 12 LD cases, nine living in different residential buildings and three nosocomial, linked by identical human and/or water isolates. Three of these cases were from January 2020, October 2020 and February 2021 and identified retrospectively. Eleven were diagnosed by urinary antigen test, 10 by PCR and five by culture; age ranged between 52 and 85 years, and 10 had underlying diseases. Nine of 12 homes of LD cases and 15 of 26 water samples from the hospital were positive for Lp 1, with concentrations up to 640,000 cfu/L. Water samples from regional storage tanks were negative. Positivity in homes and the hospital suggested inadequate maintenance measures. Enhanced surveillance combined with WGS was crucial in detecting this unusual LD outbreak related to domestic and hospital water systems. European Centre for Disease Prevention and Control (ECDC) 2023-03-16 /pmc/articles/PMC10021472/ /pubmed/36927717 http://dx.doi.org/10.2807/1560-7917.ES.2023.28.11.2200673 Text en This article is copyright of the authors or their affiliated institutions, 2023. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Outbreaks
Mentula, Silja
Kääriäinen, Sohvi
Jaakola, Sari
Niittynen, Marjo
Airaksinen, Piia
Koivula, Irma
Lehtola, Markku
Mauranen, Ella
Mononen, Isto
Savolainen, Raija
Haatainen, Susanna
Lyytikäinen, Outi
Tap water as the source of a Legionnaires’ disease outbreak spread to several residential buildings and one hospital, Finland, 2020 to 2021
title Tap water as the source of a Legionnaires’ disease outbreak spread to several residential buildings and one hospital, Finland, 2020 to 2021
title_full Tap water as the source of a Legionnaires’ disease outbreak spread to several residential buildings and one hospital, Finland, 2020 to 2021
title_fullStr Tap water as the source of a Legionnaires’ disease outbreak spread to several residential buildings and one hospital, Finland, 2020 to 2021
title_full_unstemmed Tap water as the source of a Legionnaires’ disease outbreak spread to several residential buildings and one hospital, Finland, 2020 to 2021
title_short Tap water as the source of a Legionnaires’ disease outbreak spread to several residential buildings and one hospital, Finland, 2020 to 2021
title_sort tap water as the source of a legionnaires’ disease outbreak spread to several residential buildings and one hospital, finland, 2020 to 2021
topic Outbreaks
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021472/
https://www.ncbi.nlm.nih.gov/pubmed/36927717
http://dx.doi.org/10.2807/1560-7917.ES.2023.28.11.2200673
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