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Epidemiological review of confirmed Lassa fever cases during 2016–2018, in Plateau State, North Central Nigeria

Lassa fever (LF) is endemic in West Africa and constitutes a significant public health concern due to its potential for epidemics and associated high mortality. The first reported case and management of Lassa fever in Plateau State occurred more than 50 years ago. We set out to undertake a three-yea...

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Autores principales: Gomerep, Simji, Nuwan, Martina, Butswat, Solomon, Bartekwa, Joyce, Thliza, Solomon, Akude, Christian, Omololu, Ayanfe, Shwe, David, Reyna, Rachel, Makishima, Tomoko, Paessler, Slobodan, Shehu, Nathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021590/
https://www.ncbi.nlm.nih.gov/pubmed/36962343
http://dx.doi.org/10.1371/journal.pgph.0000290
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author Gomerep, Simji
Nuwan, Martina
Butswat, Solomon
Bartekwa, Joyce
Thliza, Solomon
Akude, Christian
Omololu, Ayanfe
Shwe, David
Reyna, Rachel
Makishima, Tomoko
Paessler, Slobodan
Shehu, Nathan
author_facet Gomerep, Simji
Nuwan, Martina
Butswat, Solomon
Bartekwa, Joyce
Thliza, Solomon
Akude, Christian
Omololu, Ayanfe
Shwe, David
Reyna, Rachel
Makishima, Tomoko
Paessler, Slobodan
Shehu, Nathan
author_sort Gomerep, Simji
collection PubMed
description Lassa fever (LF) is endemic in West Africa and constitutes a significant public health concern due to its potential for epidemics and associated high mortality. The first reported case and management of Lassa fever in Plateau State occurred more than 50 years ago. We set out to undertake a three-year epidemiological review of LF cases in Plateau State, North Central Nigeria. This is a retrospective study of all confirmed LF cases in Plateau State between 2016 and 2018. Plateau state Lassa fever- Line list and patient case records were used to extract relevant data. Lassa PCR was carried out at the NCDC accredited Laboratory network. Data analysis was done using STATA version SE14.1. Forty-four persons (44) had confirmed LF over the examined period, 18 (41%) in 2016, 15 (34%) in 2017 and 11 (25%) in 2018. The mean age was 29.7±14.6 years and 53% were males. Sixty-six percent (66%) of the patients resided in rural areas. It affected all local government areas (LGA) in the state except Pankshin, Jos East and Kanke LGAs. Twenty-five percent (25%) of the cases occurred among underprivileged communities of Jos North and another 25% in rural dwellers of Langtang North. Fifty-nine percent (59%) of cases occurred during the 1(st) quarter, 27% the 2(nd) quarter and 18% the 3(rd) quarter of the year. The case fatality rate was 57%. LF is endemic in Plateau State. Prevention strategies must be sustained year round and target the youth, urban and rural underprivileged communities. There is also need for case management improvement to reduce mortality.
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spelling pubmed-100215902023-03-17 Epidemiological review of confirmed Lassa fever cases during 2016–2018, in Plateau State, North Central Nigeria Gomerep, Simji Nuwan, Martina Butswat, Solomon Bartekwa, Joyce Thliza, Solomon Akude, Christian Omololu, Ayanfe Shwe, David Reyna, Rachel Makishima, Tomoko Paessler, Slobodan Shehu, Nathan PLOS Glob Public Health Research Article Lassa fever (LF) is endemic in West Africa and constitutes a significant public health concern due to its potential for epidemics and associated high mortality. The first reported case and management of Lassa fever in Plateau State occurred more than 50 years ago. We set out to undertake a three-year epidemiological review of LF cases in Plateau State, North Central Nigeria. This is a retrospective study of all confirmed LF cases in Plateau State between 2016 and 2018. Plateau state Lassa fever- Line list and patient case records were used to extract relevant data. Lassa PCR was carried out at the NCDC accredited Laboratory network. Data analysis was done using STATA version SE14.1. Forty-four persons (44) had confirmed LF over the examined period, 18 (41%) in 2016, 15 (34%) in 2017 and 11 (25%) in 2018. The mean age was 29.7±14.6 years and 53% were males. Sixty-six percent (66%) of the patients resided in rural areas. It affected all local government areas (LGA) in the state except Pankshin, Jos East and Kanke LGAs. Twenty-five percent (25%) of the cases occurred among underprivileged communities of Jos North and another 25% in rural dwellers of Langtang North. Fifty-nine percent (59%) of cases occurred during the 1(st) quarter, 27% the 2(nd) quarter and 18% the 3(rd) quarter of the year. The case fatality rate was 57%. LF is endemic in Plateau State. Prevention strategies must be sustained year round and target the youth, urban and rural underprivileged communities. There is also need for case management improvement to reduce mortality. Public Library of Science 2022-06-24 /pmc/articles/PMC10021590/ /pubmed/36962343 http://dx.doi.org/10.1371/journal.pgph.0000290 Text en https://creativecommons.org/publicdomain/zero/1.0/This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 (https://creativecommons.org/publicdomain/zero/1.0/) public domain dedication.
spellingShingle Research Article
Gomerep, Simji
Nuwan, Martina
Butswat, Solomon
Bartekwa, Joyce
Thliza, Solomon
Akude, Christian
Omololu, Ayanfe
Shwe, David
Reyna, Rachel
Makishima, Tomoko
Paessler, Slobodan
Shehu, Nathan
Epidemiological review of confirmed Lassa fever cases during 2016–2018, in Plateau State, North Central Nigeria
title Epidemiological review of confirmed Lassa fever cases during 2016–2018, in Plateau State, North Central Nigeria
title_full Epidemiological review of confirmed Lassa fever cases during 2016–2018, in Plateau State, North Central Nigeria
title_fullStr Epidemiological review of confirmed Lassa fever cases during 2016–2018, in Plateau State, North Central Nigeria
title_full_unstemmed Epidemiological review of confirmed Lassa fever cases during 2016–2018, in Plateau State, North Central Nigeria
title_short Epidemiological review of confirmed Lassa fever cases during 2016–2018, in Plateau State, North Central Nigeria
title_sort epidemiological review of confirmed lassa fever cases during 2016–2018, in plateau state, north central nigeria
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021590/
https://www.ncbi.nlm.nih.gov/pubmed/36962343
http://dx.doi.org/10.1371/journal.pgph.0000290
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