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The rise in antimicrobial resistance: An obscure issue in COVID-19 treatment
A saturated health care system with a lack of evidence-based antiviral medicine and ignorance of antimicrobial stewardship during pandemics has prompted clinicians to prescribe a broad-spectrum antibiotic more often. A prospective, cross-sectional study of COVID-infected patients was conducted to ga...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021591/ https://www.ncbi.nlm.nih.gov/pubmed/36962458 http://dx.doi.org/10.1371/journal.pgph.0000641 |
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author | Shrestha, Yogendra Shivalingegowda, Ravi Kurikempannadoddi Avinash, Melkote Jyotiprakash Kenchegowda, Sharath Babu Hagalahalli Moktan, Jeet Bahadur Doddasamiah, Sreenivas Murthy Tambat, Ramesh Mahadev Golshetty, Deepanjali Girish Ganesh, Vakkalagadda Siva Venkataraman, Rajesh |
author_facet | Shrestha, Yogendra Shivalingegowda, Ravi Kurikempannadoddi Avinash, Melkote Jyotiprakash Kenchegowda, Sharath Babu Hagalahalli Moktan, Jeet Bahadur Doddasamiah, Sreenivas Murthy Tambat, Ramesh Mahadev Golshetty, Deepanjali Girish Ganesh, Vakkalagadda Siva Venkataraman, Rajesh |
author_sort | Shrestha, Yogendra |
collection | PubMed |
description | A saturated health care system with a lack of evidence-based antiviral medicine and ignorance of antimicrobial stewardship during pandemics has prompted clinicians to prescribe a broad-spectrum antibiotic more often. A prospective, cross-sectional study of COVID-infected patients was conducted to gain insight into antibiotic prescribing practices and their impact on antimicrobial resistance. The antibiotic susceptibility test was performed using the disc diffusion method. 318 patients met the study’s inclusion criteria, with a mean age of 46 years and 55% (175) of them being males. Antibiotics were prescribed for 93.72% (209) of mild cases, 92.45% (49) of moderate cases, 96.15% (25) of severe cases, and 100% (16) of critical cases of COVID-19. A total of 95 samples were sent in for culture and antibiotic sensitivity testing, with 58.95% (56) confirming growth. The majority of the growth was found to contain E. coli (14). In 54.9% of cases, antibiotics with less than 50% sensitivity to curing bacterial infection were detected. In the study, we found that antibiotics were being used unnecessarily in excessive quantities and that more than half of the antibiotics were less sensitive to isolated bacteria. |
format | Online Article Text |
id | pubmed-10021591 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-100215912023-03-17 The rise in antimicrobial resistance: An obscure issue in COVID-19 treatment Shrestha, Yogendra Shivalingegowda, Ravi Kurikempannadoddi Avinash, Melkote Jyotiprakash Kenchegowda, Sharath Babu Hagalahalli Moktan, Jeet Bahadur Doddasamiah, Sreenivas Murthy Tambat, Ramesh Mahadev Golshetty, Deepanjali Girish Ganesh, Vakkalagadda Siva Venkataraman, Rajesh PLOS Glob Public Health Research Article A saturated health care system with a lack of evidence-based antiviral medicine and ignorance of antimicrobial stewardship during pandemics has prompted clinicians to prescribe a broad-spectrum antibiotic more often. A prospective, cross-sectional study of COVID-infected patients was conducted to gain insight into antibiotic prescribing practices and their impact on antimicrobial resistance. The antibiotic susceptibility test was performed using the disc diffusion method. 318 patients met the study’s inclusion criteria, with a mean age of 46 years and 55% (175) of them being males. Antibiotics were prescribed for 93.72% (209) of mild cases, 92.45% (49) of moderate cases, 96.15% (25) of severe cases, and 100% (16) of critical cases of COVID-19. A total of 95 samples were sent in for culture and antibiotic sensitivity testing, with 58.95% (56) confirming growth. The majority of the growth was found to contain E. coli (14). In 54.9% of cases, antibiotics with less than 50% sensitivity to curing bacterial infection were detected. In the study, we found that antibiotics were being used unnecessarily in excessive quantities and that more than half of the antibiotics were less sensitive to isolated bacteria. Public Library of Science 2022-07-13 /pmc/articles/PMC10021591/ /pubmed/36962458 http://dx.doi.org/10.1371/journal.pgph.0000641 Text en © 2022 Shrestha et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Shrestha, Yogendra Shivalingegowda, Ravi Kurikempannadoddi Avinash, Melkote Jyotiprakash Kenchegowda, Sharath Babu Hagalahalli Moktan, Jeet Bahadur Doddasamiah, Sreenivas Murthy Tambat, Ramesh Mahadev Golshetty, Deepanjali Girish Ganesh, Vakkalagadda Siva Venkataraman, Rajesh The rise in antimicrobial resistance: An obscure issue in COVID-19 treatment |
title | The rise in antimicrobial resistance: An obscure issue in COVID-19 treatment |
title_full | The rise in antimicrobial resistance: An obscure issue in COVID-19 treatment |
title_fullStr | The rise in antimicrobial resistance: An obscure issue in COVID-19 treatment |
title_full_unstemmed | The rise in antimicrobial resistance: An obscure issue in COVID-19 treatment |
title_short | The rise in antimicrobial resistance: An obscure issue in COVID-19 treatment |
title_sort | rise in antimicrobial resistance: an obscure issue in covid-19 treatment |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021591/ https://www.ncbi.nlm.nih.gov/pubmed/36962458 http://dx.doi.org/10.1371/journal.pgph.0000641 |
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