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Prevalence and factors associated with anogenital warts among sexual and gender minorities attending a trusted community health center in Lagos, Nigeria

Anogenital warts caused by human papillomavirus are common in sexual and gender minorities (SGM). The prevalence of, and factors associated with warts were described for SGM with a high burden of HIV in Nigeria. Individuals who reported anal sex with men were enrolled in the TRUST/RV368 cohort. Part...

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Autores principales: Adebajo, Sylvia B., Nowak, Rebecca G., Adebiyi, Ruxton, Shoyemi, Elizabeth, Ekeh, Charles, Ramadhani, Habib O., Gaydos, Charlotte A., Ake, Julie A., Baral, Stefan D., Charurat, Manhattan E., Crowell, Trevor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021808/
https://www.ncbi.nlm.nih.gov/pubmed/36962635
http://dx.doi.org/10.1371/journal.pgph.0001215
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author Adebajo, Sylvia B.
Nowak, Rebecca G.
Adebiyi, Ruxton
Shoyemi, Elizabeth
Ekeh, Charles
Ramadhani, Habib O.
Gaydos, Charlotte A.
Ake, Julie A.
Baral, Stefan D.
Charurat, Manhattan E.
Crowell, Trevor A.
author_facet Adebajo, Sylvia B.
Nowak, Rebecca G.
Adebiyi, Ruxton
Shoyemi, Elizabeth
Ekeh, Charles
Ramadhani, Habib O.
Gaydos, Charlotte A.
Ake, Julie A.
Baral, Stefan D.
Charurat, Manhattan E.
Crowell, Trevor A.
author_sort Adebajo, Sylvia B.
collection PubMed
description Anogenital warts caused by human papillomavirus are common in sexual and gender minorities (SGM). The prevalence of, and factors associated with warts were described for SGM with a high burden of HIV in Nigeria. Individuals who reported anal sex with men were enrolled in the TRUST/RV368 cohort. Participants completed an interviewer-led survey, provided biological samples, and had a physical examination. Specific to the Lagos site, clinic staff offered standardized warts treatment services. RDS-weighted multivariable logistic regression was used to estimate the adjusted odds ratios (AORs) and 95% confidence intervals (CIs) for factors potentially associated with anogenital warts. Of 672 enrolled SGM, 478 (71%) engaged in warts services and had complete data. The median age (interquartile range) was 22 (20–26) years, 272 (52%) initiated sex before age 18, and 347 (79%) were cisgender men. Multiple male sexual partners in the previous year were reported by 448 (90%) of the participants, and 342 (66%) were living with HIV. Warts were diagnosed in 252 (54%), including anal warts in 234 (43%) and penile warts in 44 (8%); 26 (5%) had both anal and penile warts. Factors independently associated with warts included HIV (AOR:2.97; CI:1.44–6.14), engaging in receptive anal sex (AOR:3.49; CI:1.25–9.75), having multiple male sexual partners (AOR:7.26; CI:2.11–24.87), age at sexual debut (AOR:0.53; CI:0.28–0.98), and non-binary gender identity (AOR:0.20; CI:0.05–0.71). Warts were common among SGM in Nigeria, particularly those living with HIV. Administration of HPV vaccination before sexual debut or as a catch-up vaccination may prevent HPV-associated complications.
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spelling pubmed-100218082023-03-17 Prevalence and factors associated with anogenital warts among sexual and gender minorities attending a trusted community health center in Lagos, Nigeria Adebajo, Sylvia B. Nowak, Rebecca G. Adebiyi, Ruxton Shoyemi, Elizabeth Ekeh, Charles Ramadhani, Habib O. Gaydos, Charlotte A. Ake, Julie A. Baral, Stefan D. Charurat, Manhattan E. Crowell, Trevor A. PLOS Glob Public Health Research Article Anogenital warts caused by human papillomavirus are common in sexual and gender minorities (SGM). The prevalence of, and factors associated with warts were described for SGM with a high burden of HIV in Nigeria. Individuals who reported anal sex with men were enrolled in the TRUST/RV368 cohort. Participants completed an interviewer-led survey, provided biological samples, and had a physical examination. Specific to the Lagos site, clinic staff offered standardized warts treatment services. RDS-weighted multivariable logistic regression was used to estimate the adjusted odds ratios (AORs) and 95% confidence intervals (CIs) for factors potentially associated with anogenital warts. Of 672 enrolled SGM, 478 (71%) engaged in warts services and had complete data. The median age (interquartile range) was 22 (20–26) years, 272 (52%) initiated sex before age 18, and 347 (79%) were cisgender men. Multiple male sexual partners in the previous year were reported by 448 (90%) of the participants, and 342 (66%) were living with HIV. Warts were diagnosed in 252 (54%), including anal warts in 234 (43%) and penile warts in 44 (8%); 26 (5%) had both anal and penile warts. Factors independently associated with warts included HIV (AOR:2.97; CI:1.44–6.14), engaging in receptive anal sex (AOR:3.49; CI:1.25–9.75), having multiple male sexual partners (AOR:7.26; CI:2.11–24.87), age at sexual debut (AOR:0.53; CI:0.28–0.98), and non-binary gender identity (AOR:0.20; CI:0.05–0.71). Warts were common among SGM in Nigeria, particularly those living with HIV. Administration of HPV vaccination before sexual debut or as a catch-up vaccination may prevent HPV-associated complications. Public Library of Science 2022-11-08 /pmc/articles/PMC10021808/ /pubmed/36962635 http://dx.doi.org/10.1371/journal.pgph.0001215 Text en https://creativecommons.org/publicdomain/zero/1.0/This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 (https://creativecommons.org/publicdomain/zero/1.0/) public domain dedication.
spellingShingle Research Article
Adebajo, Sylvia B.
Nowak, Rebecca G.
Adebiyi, Ruxton
Shoyemi, Elizabeth
Ekeh, Charles
Ramadhani, Habib O.
Gaydos, Charlotte A.
Ake, Julie A.
Baral, Stefan D.
Charurat, Manhattan E.
Crowell, Trevor A.
Prevalence and factors associated with anogenital warts among sexual and gender minorities attending a trusted community health center in Lagos, Nigeria
title Prevalence and factors associated with anogenital warts among sexual and gender minorities attending a trusted community health center in Lagos, Nigeria
title_full Prevalence and factors associated with anogenital warts among sexual and gender minorities attending a trusted community health center in Lagos, Nigeria
title_fullStr Prevalence and factors associated with anogenital warts among sexual and gender minorities attending a trusted community health center in Lagos, Nigeria
title_full_unstemmed Prevalence and factors associated with anogenital warts among sexual and gender minorities attending a trusted community health center in Lagos, Nigeria
title_short Prevalence and factors associated with anogenital warts among sexual and gender minorities attending a trusted community health center in Lagos, Nigeria
title_sort prevalence and factors associated with anogenital warts among sexual and gender minorities attending a trusted community health center in lagos, nigeria
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021808/
https://www.ncbi.nlm.nih.gov/pubmed/36962635
http://dx.doi.org/10.1371/journal.pgph.0001215
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