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Lessons from a pandemic

Several interventions have been used around the world trying to contain the SARS-CoV-2 pandemic, such as quarantine, prohibition of mass demonstrations, isolation of sick people, tracing of virus carriers, semi-containment, promotion of barrier gestures, development of rapid self-tests and vaccines...

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Detalles Bibliográficos
Autores principales: Eggli, Yves, Rousson, Valentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021850/
https://www.ncbi.nlm.nih.gov/pubmed/36962218
http://dx.doi.org/10.1371/journal.pgph.0000404
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author Eggli, Yves
Rousson, Valentin
author_facet Eggli, Yves
Rousson, Valentin
author_sort Eggli, Yves
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description Several interventions have been used around the world trying to contain the SARS-CoV-2 pandemic, such as quarantine, prohibition of mass demonstrations, isolation of sick people, tracing of virus carriers, semi-containment, promotion of barrier gestures, development of rapid self-tests and vaccines among others. We propose a simple model to evaluate the potential impact of such interventions. A model for the reproduction number of an infectious disease including three main contexts of infection (indoor mass events, public indoor activities and household) and seven parameters is considered. We illustrate how these parameters could be obtained from the literature or from expert assumptions, and we apply the model to describe 20 scenarios that can typically occur during the different phases of a pandemic. This model provides a useful framework for better understanding and communicating the effects of different (combinations of) possible interventions, while encouraging constant updating of expert assumptions to better match reality. This simple approach will bring more transparency and public support to help governments to think, decide, evaluate and adjust what to do during a pandemic.
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spelling pubmed-100218502023-03-17 Lessons from a pandemic Eggli, Yves Rousson, Valentin PLOS Glob Public Health Research Article Several interventions have been used around the world trying to contain the SARS-CoV-2 pandemic, such as quarantine, prohibition of mass demonstrations, isolation of sick people, tracing of virus carriers, semi-containment, promotion of barrier gestures, development of rapid self-tests and vaccines among others. We propose a simple model to evaluate the potential impact of such interventions. A model for the reproduction number of an infectious disease including three main contexts of infection (indoor mass events, public indoor activities and household) and seven parameters is considered. We illustrate how these parameters could be obtained from the literature or from expert assumptions, and we apply the model to describe 20 scenarios that can typically occur during the different phases of a pandemic. This model provides a useful framework for better understanding and communicating the effects of different (combinations of) possible interventions, while encouraging constant updating of expert assumptions to better match reality. This simple approach will bring more transparency and public support to help governments to think, decide, evaluate and adjust what to do during a pandemic. Public Library of Science 2022-07-22 /pmc/articles/PMC10021850/ /pubmed/36962218 http://dx.doi.org/10.1371/journal.pgph.0000404 Text en © 2022 Eggli, Rousson https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Eggli, Yves
Rousson, Valentin
Lessons from a pandemic
title Lessons from a pandemic
title_full Lessons from a pandemic
title_fullStr Lessons from a pandemic
title_full_unstemmed Lessons from a pandemic
title_short Lessons from a pandemic
title_sort lessons from a pandemic
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021850/
https://www.ncbi.nlm.nih.gov/pubmed/36962218
http://dx.doi.org/10.1371/journal.pgph.0000404
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