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Epidemiological and virological factors determining dengue transmission in Sri Lanka during the COVID-19 pandemic
With the onset of the COVID-19 pandemic in early 2020 there was a drastic reduction in the number of dengue cases in Sri Lanka, with an increase towards the end of 2021. We sought to study the contribution of virological factors, human mobility, school closure and mosquito factors in affecting these...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021909/ https://www.ncbi.nlm.nih.gov/pubmed/36962516 http://dx.doi.org/10.1371/journal.pgph.0000399 |
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author | Ariyaratne, Dinuka Gomes, Laksiri Jayadas, Tibutius T. P. Kuruppu, Heshan Kodituwakku, Lahiru Jeewandara, Chandima Pannila Hetti, Nimalka Dheerasinghe, Anoja Samaraweera, Sudath Ogg, Graham S. Malavige, Gathsaurie Neelika |
author_facet | Ariyaratne, Dinuka Gomes, Laksiri Jayadas, Tibutius T. P. Kuruppu, Heshan Kodituwakku, Lahiru Jeewandara, Chandima Pannila Hetti, Nimalka Dheerasinghe, Anoja Samaraweera, Sudath Ogg, Graham S. Malavige, Gathsaurie Neelika |
author_sort | Ariyaratne, Dinuka |
collection | PubMed |
description | With the onset of the COVID-19 pandemic in early 2020 there was a drastic reduction in the number of dengue cases in Sri Lanka, with an increase towards the end of 2021. We sought to study the contribution of virological factors, human mobility, school closure and mosquito factors in affecting these changes in dengue transmission in Sri Lanka during this time. To understand the reasons for the differences in the dengue case numbers in 2020 to 2021 compared to previous years, we determined the association between the case numbers in Colombo (which has continuously reported the highest number of cases) with school closures, stringency index, changes in dengue virus (DENV) serotypes and vector densities. There was a 79.4% drop in dengue cases from 2019 to 2020 in Colombo. A significant negative correlation was seen with the number of cases and school closures (Spearman’s r = -0.4732, p <0.0001) and a negative correlation, which was not significant, between the stringency index and case numbers (Spearman’s r = -0.3755 p = 0.0587). There was no change in the circulating DENV serotypes with DENV2 remaining the most prevalent serotype by early 2022 (65%), similar to the frequencies observed by end of 2019. The Aedes aegypti premise and container indices showed positive but insignificant correlations with dengue case numbers (Spearman r = 0.8827, p = 0.93). Lockdown measures, especially school closures seemed to have had a significant impact on the number of dengue cases, while the vector indices had a limited effect. |
format | Online Article Text |
id | pubmed-10021909 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-100219092023-03-17 Epidemiological and virological factors determining dengue transmission in Sri Lanka during the COVID-19 pandemic Ariyaratne, Dinuka Gomes, Laksiri Jayadas, Tibutius T. P. Kuruppu, Heshan Kodituwakku, Lahiru Jeewandara, Chandima Pannila Hetti, Nimalka Dheerasinghe, Anoja Samaraweera, Sudath Ogg, Graham S. Malavige, Gathsaurie Neelika PLOS Glob Public Health Research Article With the onset of the COVID-19 pandemic in early 2020 there was a drastic reduction in the number of dengue cases in Sri Lanka, with an increase towards the end of 2021. We sought to study the contribution of virological factors, human mobility, school closure and mosquito factors in affecting these changes in dengue transmission in Sri Lanka during this time. To understand the reasons for the differences in the dengue case numbers in 2020 to 2021 compared to previous years, we determined the association between the case numbers in Colombo (which has continuously reported the highest number of cases) with school closures, stringency index, changes in dengue virus (DENV) serotypes and vector densities. There was a 79.4% drop in dengue cases from 2019 to 2020 in Colombo. A significant negative correlation was seen with the number of cases and school closures (Spearman’s r = -0.4732, p <0.0001) and a negative correlation, which was not significant, between the stringency index and case numbers (Spearman’s r = -0.3755 p = 0.0587). There was no change in the circulating DENV serotypes with DENV2 remaining the most prevalent serotype by early 2022 (65%), similar to the frequencies observed by end of 2019. The Aedes aegypti premise and container indices showed positive but insignificant correlations with dengue case numbers (Spearman r = 0.8827, p = 0.93). Lockdown measures, especially school closures seemed to have had a significant impact on the number of dengue cases, while the vector indices had a limited effect. Public Library of Science 2022-08-03 /pmc/articles/PMC10021909/ /pubmed/36962516 http://dx.doi.org/10.1371/journal.pgph.0000399 Text en © 2022 Ariyaratne et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Ariyaratne, Dinuka Gomes, Laksiri Jayadas, Tibutius T. P. Kuruppu, Heshan Kodituwakku, Lahiru Jeewandara, Chandima Pannila Hetti, Nimalka Dheerasinghe, Anoja Samaraweera, Sudath Ogg, Graham S. Malavige, Gathsaurie Neelika Epidemiological and virological factors determining dengue transmission in Sri Lanka during the COVID-19 pandemic |
title | Epidemiological and virological factors determining dengue transmission in Sri Lanka during the COVID-19 pandemic |
title_full | Epidemiological and virological factors determining dengue transmission in Sri Lanka during the COVID-19 pandemic |
title_fullStr | Epidemiological and virological factors determining dengue transmission in Sri Lanka during the COVID-19 pandemic |
title_full_unstemmed | Epidemiological and virological factors determining dengue transmission in Sri Lanka during the COVID-19 pandemic |
title_short | Epidemiological and virological factors determining dengue transmission in Sri Lanka during the COVID-19 pandemic |
title_sort | epidemiological and virological factors determining dengue transmission in sri lanka during the covid-19 pandemic |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021909/ https://www.ncbi.nlm.nih.gov/pubmed/36962516 http://dx.doi.org/10.1371/journal.pgph.0000399 |
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