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Epidemiological and virological factors determining dengue transmission in Sri Lanka during the COVID-19 pandemic

With the onset of the COVID-19 pandemic in early 2020 there was a drastic reduction in the number of dengue cases in Sri Lanka, with an increase towards the end of 2021. We sought to study the contribution of virological factors, human mobility, school closure and mosquito factors in affecting these...

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Autores principales: Ariyaratne, Dinuka, Gomes, Laksiri, Jayadas, Tibutius T. P., Kuruppu, Heshan, Kodituwakku, Lahiru, Jeewandara, Chandima, Pannila Hetti, Nimalka, Dheerasinghe, Anoja, Samaraweera, Sudath, Ogg, Graham S., Malavige, Gathsaurie Neelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021909/
https://www.ncbi.nlm.nih.gov/pubmed/36962516
http://dx.doi.org/10.1371/journal.pgph.0000399
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author Ariyaratne, Dinuka
Gomes, Laksiri
Jayadas, Tibutius T. P.
Kuruppu, Heshan
Kodituwakku, Lahiru
Jeewandara, Chandima
Pannila Hetti, Nimalka
Dheerasinghe, Anoja
Samaraweera, Sudath
Ogg, Graham S.
Malavige, Gathsaurie Neelika
author_facet Ariyaratne, Dinuka
Gomes, Laksiri
Jayadas, Tibutius T. P.
Kuruppu, Heshan
Kodituwakku, Lahiru
Jeewandara, Chandima
Pannila Hetti, Nimalka
Dheerasinghe, Anoja
Samaraweera, Sudath
Ogg, Graham S.
Malavige, Gathsaurie Neelika
author_sort Ariyaratne, Dinuka
collection PubMed
description With the onset of the COVID-19 pandemic in early 2020 there was a drastic reduction in the number of dengue cases in Sri Lanka, with an increase towards the end of 2021. We sought to study the contribution of virological factors, human mobility, school closure and mosquito factors in affecting these changes in dengue transmission in Sri Lanka during this time. To understand the reasons for the differences in the dengue case numbers in 2020 to 2021 compared to previous years, we determined the association between the case numbers in Colombo (which has continuously reported the highest number of cases) with school closures, stringency index, changes in dengue virus (DENV) serotypes and vector densities. There was a 79.4% drop in dengue cases from 2019 to 2020 in Colombo. A significant negative correlation was seen with the number of cases and school closures (Spearman’s r = -0.4732, p <0.0001) and a negative correlation, which was not significant, between the stringency index and case numbers (Spearman’s r = -0.3755 p = 0.0587). There was no change in the circulating DENV serotypes with DENV2 remaining the most prevalent serotype by early 2022 (65%), similar to the frequencies observed by end of 2019. The Aedes aegypti premise and container indices showed positive but insignificant correlations with dengue case numbers (Spearman r = 0.8827, p = 0.93). Lockdown measures, especially school closures seemed to have had a significant impact on the number of dengue cases, while the vector indices had a limited effect.
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spelling pubmed-100219092023-03-17 Epidemiological and virological factors determining dengue transmission in Sri Lanka during the COVID-19 pandemic Ariyaratne, Dinuka Gomes, Laksiri Jayadas, Tibutius T. P. Kuruppu, Heshan Kodituwakku, Lahiru Jeewandara, Chandima Pannila Hetti, Nimalka Dheerasinghe, Anoja Samaraweera, Sudath Ogg, Graham S. Malavige, Gathsaurie Neelika PLOS Glob Public Health Research Article With the onset of the COVID-19 pandemic in early 2020 there was a drastic reduction in the number of dengue cases in Sri Lanka, with an increase towards the end of 2021. We sought to study the contribution of virological factors, human mobility, school closure and mosquito factors in affecting these changes in dengue transmission in Sri Lanka during this time. To understand the reasons for the differences in the dengue case numbers in 2020 to 2021 compared to previous years, we determined the association between the case numbers in Colombo (which has continuously reported the highest number of cases) with school closures, stringency index, changes in dengue virus (DENV) serotypes and vector densities. There was a 79.4% drop in dengue cases from 2019 to 2020 in Colombo. A significant negative correlation was seen with the number of cases and school closures (Spearman’s r = -0.4732, p <0.0001) and a negative correlation, which was not significant, between the stringency index and case numbers (Spearman’s r = -0.3755 p = 0.0587). There was no change in the circulating DENV serotypes with DENV2 remaining the most prevalent serotype by early 2022 (65%), similar to the frequencies observed by end of 2019. The Aedes aegypti premise and container indices showed positive but insignificant correlations with dengue case numbers (Spearman r = 0.8827, p = 0.93). Lockdown measures, especially school closures seemed to have had a significant impact on the number of dengue cases, while the vector indices had a limited effect. Public Library of Science 2022-08-03 /pmc/articles/PMC10021909/ /pubmed/36962516 http://dx.doi.org/10.1371/journal.pgph.0000399 Text en © 2022 Ariyaratne et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Ariyaratne, Dinuka
Gomes, Laksiri
Jayadas, Tibutius T. P.
Kuruppu, Heshan
Kodituwakku, Lahiru
Jeewandara, Chandima
Pannila Hetti, Nimalka
Dheerasinghe, Anoja
Samaraweera, Sudath
Ogg, Graham S.
Malavige, Gathsaurie Neelika
Epidemiological and virological factors determining dengue transmission in Sri Lanka during the COVID-19 pandemic
title Epidemiological and virological factors determining dengue transmission in Sri Lanka during the COVID-19 pandemic
title_full Epidemiological and virological factors determining dengue transmission in Sri Lanka during the COVID-19 pandemic
title_fullStr Epidemiological and virological factors determining dengue transmission in Sri Lanka during the COVID-19 pandemic
title_full_unstemmed Epidemiological and virological factors determining dengue transmission in Sri Lanka during the COVID-19 pandemic
title_short Epidemiological and virological factors determining dengue transmission in Sri Lanka during the COVID-19 pandemic
title_sort epidemiological and virological factors determining dengue transmission in sri lanka during the covid-19 pandemic
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021909/
https://www.ncbi.nlm.nih.gov/pubmed/36962516
http://dx.doi.org/10.1371/journal.pgph.0000399
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