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Life expectancy among older adults with or without frailty in China: multistate modelling of a national longitudinal cohort study
BACKGROUND: Little is known about life expectancy (LE) with or without frailty. We aimed to estimate the total LE and duration of the state of frailty in China. METHODS: This study included older adults aged 65 years and older from the Chinese Longitudinal Healthy Longevity Study (CLHLS). Frailty st...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021933/ https://www.ncbi.nlm.nih.gov/pubmed/36927351 http://dx.doi.org/10.1186/s12916-023-02825-7 |
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author | Gao, Junling Wang, Yujie Xu, Jixiang Jiang, Junjia Yang, Shitong Xiao, Qianyi |
author_facet | Gao, Junling Wang, Yujie Xu, Jixiang Jiang, Junjia Yang, Shitong Xiao, Qianyi |
author_sort | Gao, Junling |
collection | PubMed |
description | BACKGROUND: Little is known about life expectancy (LE) with or without frailty. We aimed to estimate the total LE and duration of the state of frailty in China. METHODS: This study included older adults aged 65 years and older from the Chinese Longitudinal Healthy Longevity Study (CLHLS). Frailty status was classified into robust, pre-frailty and frailty based on a cumulative deficit model. Total and specific frailty state LEs at 65 years of age were estimated and stratified by demographic characteristics, behaviours, and psychosocial factors using continuous-time multistate modelling. RESULTS: The total LE of older adults aged 65 years in China was 14.74 years on average (95% CI: 14.52–14.94), of which 4.18 years (95% CI: 4.05–4.30) were robust, 7.46 years (95% CI: 7.31–7.61) pre-frail and 3.10 years (95% CI: 3.01–3.20) frail. Older adults with higher robust LE included men (4.71 years, 95% CI: 4.56–4.88), married older adults (4.41 years, 95% CI: 4.27–4.56), those engaging in physical activity (4.41 years, 95% CI: 4.23–4.59), those consuming fruits daily (4.48 years, 95% CI: 4.22–4.77) and those with high social participation (4.39 years, 95% CI: 4.26–4.53). Increased educational attainment were gradually associated with increased robust LE. CONCLUSIONS: Frailty may lead to a reduced total LE and robust LE of older adults in China. In addition to finding inequalities in total and robust LEs by socioeconomic status, our findings also highlight that healthy behaviours and social participation may ease frailty-related reductions in total and robust LE. Our findings imply that national life-course strategies aimed at frailty screening and psychosocial and behavioural interventions could be important for health aging in China. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12916-023-02825-7. |
format | Online Article Text |
id | pubmed-10021933 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-100219332023-03-18 Life expectancy among older adults with or without frailty in China: multistate modelling of a national longitudinal cohort study Gao, Junling Wang, Yujie Xu, Jixiang Jiang, Junjia Yang, Shitong Xiao, Qianyi BMC Med Research Article BACKGROUND: Little is known about life expectancy (LE) with or without frailty. We aimed to estimate the total LE and duration of the state of frailty in China. METHODS: This study included older adults aged 65 years and older from the Chinese Longitudinal Healthy Longevity Study (CLHLS). Frailty status was classified into robust, pre-frailty and frailty based on a cumulative deficit model. Total and specific frailty state LEs at 65 years of age were estimated and stratified by demographic characteristics, behaviours, and psychosocial factors using continuous-time multistate modelling. RESULTS: The total LE of older adults aged 65 years in China was 14.74 years on average (95% CI: 14.52–14.94), of which 4.18 years (95% CI: 4.05–4.30) were robust, 7.46 years (95% CI: 7.31–7.61) pre-frail and 3.10 years (95% CI: 3.01–3.20) frail. Older adults with higher robust LE included men (4.71 years, 95% CI: 4.56–4.88), married older adults (4.41 years, 95% CI: 4.27–4.56), those engaging in physical activity (4.41 years, 95% CI: 4.23–4.59), those consuming fruits daily (4.48 years, 95% CI: 4.22–4.77) and those with high social participation (4.39 years, 95% CI: 4.26–4.53). Increased educational attainment were gradually associated with increased robust LE. CONCLUSIONS: Frailty may lead to a reduced total LE and robust LE of older adults in China. In addition to finding inequalities in total and robust LEs by socioeconomic status, our findings also highlight that healthy behaviours and social participation may ease frailty-related reductions in total and robust LE. Our findings imply that national life-course strategies aimed at frailty screening and psychosocial and behavioural interventions could be important for health aging in China. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12916-023-02825-7. BioMed Central 2023-03-16 /pmc/articles/PMC10021933/ /pubmed/36927351 http://dx.doi.org/10.1186/s12916-023-02825-7 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Article Gao, Junling Wang, Yujie Xu, Jixiang Jiang, Junjia Yang, Shitong Xiao, Qianyi Life expectancy among older adults with or without frailty in China: multistate modelling of a national longitudinal cohort study |
title | Life expectancy among older adults with or without frailty in China: multistate modelling of a national longitudinal cohort study |
title_full | Life expectancy among older adults with or without frailty in China: multistate modelling of a national longitudinal cohort study |
title_fullStr | Life expectancy among older adults with or without frailty in China: multistate modelling of a national longitudinal cohort study |
title_full_unstemmed | Life expectancy among older adults with or without frailty in China: multistate modelling of a national longitudinal cohort study |
title_short | Life expectancy among older adults with or without frailty in China: multistate modelling of a national longitudinal cohort study |
title_sort | life expectancy among older adults with or without frailty in china: multistate modelling of a national longitudinal cohort study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021933/ https://www.ncbi.nlm.nih.gov/pubmed/36927351 http://dx.doi.org/10.1186/s12916-023-02825-7 |
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