Grpel2 maintains cardiomyocyte survival in diabetic cardiomyopathy through DLST-mediated mitochondrial dysfunction: a proof-of-concept study

BACKGROUND: Diabetic cardiomyopathy (DCM) has been considered as a major threat to health in individuals with diabetes. GrpE-like 2 (Grpel2), a nucleotide exchange factor, has been shown to regulate mitochondrial import process to maintain mitochondrial homeostasis. However, the effect and mechanism...

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Detalles Bibliográficos
Autores principales: Yang, Rongjin, Zhang, Xiaomeng, Zhang, Yunyun, Wang, Yingfan, Li, Man, Meng, Yuancui, Wang, Jianbang, Wen, Xue, Yu, Jun, Chang, Pan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021968/
https://www.ncbi.nlm.nih.gov/pubmed/36927450
http://dx.doi.org/10.1186/s12967-023-04049-y

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