Verification of prognostic expression biomarkers is improved by examining enriched leukemic blasts rather than mononuclear cells from acute myeloid leukemia patients

BACKGROUND: Studies have not systematically compared the ability to verify performance of prognostic transcripts in paired bulk mononuclear cells versus viable CD34-expressing leukemic blasts from patients with acute myeloid leukemia. We hypothesized that examining the homogenous leukemic blasts wil...

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Detalles Bibliográficos
Autores principales: Pogosova-Agadjanyan, Era L., Hua, Xing, Othus, Megan, Appelbaum, Frederick R., Chauncey, Thomas R., Erba, Harry P., Fitzgibbon, Matthew P., Jenkins, Isaac C., Fang, Min, Lee, Stanley C., Moseley, Anna, Naru, Jasmine, Radich, Jerald P., Smith, Jenny L., Willborg, Brooke E., Willman, Cheryl L., Wu, Feinan, Meshinchi, Soheil, Stirewalt, Derek L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022072/
https://www.ncbi.nlm.nih.gov/pubmed/36927800
http://dx.doi.org/10.1186/s40364-023-00461-0

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