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Post-COVID-19 syndrome risk factors and further use of health services in East England

Post-COVID syndrome, defined as symptoms persisting for more than twelve weeks after the diagnosis of COVID-19, has been recognised as a new clinical entity in the context of SARS-CoV-2 infection. This study was conducted to characterise the burden and predictors for post-COVID-19 syndrome in the lo...

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Autores principales: Debski, Maciej, Tsampasian, Vasiliki, Haney, Shawn, Blakely, Katy, Weston, Samantha, Ntatsaki, Eleana, Lim, Mark, Madden, Susan, Perperoglou, Aris, Vassiliou, Vassilios S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022108/
https://www.ncbi.nlm.nih.gov/pubmed/36962824
http://dx.doi.org/10.1371/journal.pgph.0001188
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author Debski, Maciej
Tsampasian, Vasiliki
Haney, Shawn
Blakely, Katy
Weston, Samantha
Ntatsaki, Eleana
Lim, Mark
Madden, Susan
Perperoglou, Aris
Vassiliou, Vassilios S.
author_facet Debski, Maciej
Tsampasian, Vasiliki
Haney, Shawn
Blakely, Katy
Weston, Samantha
Ntatsaki, Eleana
Lim, Mark
Madden, Susan
Perperoglou, Aris
Vassiliou, Vassilios S.
author_sort Debski, Maciej
collection PubMed
description Post-COVID syndrome, defined as symptoms persisting for more than twelve weeks after the diagnosis of COVID-19, has been recognised as a new clinical entity in the context of SARS-CoV-2 infection. This study was conducted to characterise the burden and predictors for post-COVID-19 syndrome in the local population. It was a community-based web-survey study conducted in Norfolk, East England, UK. We sent the survey to patients with confirmed COVID-19 infection by real-time polymerase chain reaction by December 6th, 2020. Questions related to the pre-COVID and post-COVID level of symptoms and further healthcare use. Baseline characteristics were collected from the primary care records. Logistic regression analysis was conducted to establish predictors for post-COVID-19 syndrome and further healthcare utilisation. Of 6,318 patients, survey responses were obtained from 1,487 participants (23.5%). Post-COVID-19 syndrome symptoms were experienced by 774 (52.1%) respondents. Male sex compared to female sex was a factor protective of post-COVID symptoms; relative risk (RR) 0.748, 95% confidence interval (CI), 0.605–0.924. Body mass index was associated with a greater risk of developing post-COVID-19 symptoms (RR 1.031, 95% CI, 1.016–1.047, for 1 kg/m2). A total of 378 (25.4%) people used further health services after their index COVID-19 infection, of whom 277 (73.2%) had post-COVID symptoms. Male sex was negatively associated with the use of further health services (RR 0.618, 95% CI, 0.464–0.818) whereas BMI was positively associated (RR 1.027, 95% CI, 1.009–1.046). Overall, post-COVID-19 symptoms increased the probability of using health services with RR 3.280, 95% CI, 2.540–4.262. This survey of a large number of people previously diagnosed with COVID-19 across East England shows a high prevalence of self-reported post-COVID-19 syndrome. Female sex and BMI were associated with an increased risk of post-COVID-19 syndrome and further utilisation of healthcare.
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spelling pubmed-100221082023-03-17 Post-COVID-19 syndrome risk factors and further use of health services in East England Debski, Maciej Tsampasian, Vasiliki Haney, Shawn Blakely, Katy Weston, Samantha Ntatsaki, Eleana Lim, Mark Madden, Susan Perperoglou, Aris Vassiliou, Vassilios S. PLOS Glob Public Health Research Article Post-COVID syndrome, defined as symptoms persisting for more than twelve weeks after the diagnosis of COVID-19, has been recognised as a new clinical entity in the context of SARS-CoV-2 infection. This study was conducted to characterise the burden and predictors for post-COVID-19 syndrome in the local population. It was a community-based web-survey study conducted in Norfolk, East England, UK. We sent the survey to patients with confirmed COVID-19 infection by real-time polymerase chain reaction by December 6th, 2020. Questions related to the pre-COVID and post-COVID level of symptoms and further healthcare use. Baseline characteristics were collected from the primary care records. Logistic regression analysis was conducted to establish predictors for post-COVID-19 syndrome and further healthcare utilisation. Of 6,318 patients, survey responses were obtained from 1,487 participants (23.5%). Post-COVID-19 syndrome symptoms were experienced by 774 (52.1%) respondents. Male sex compared to female sex was a factor protective of post-COVID symptoms; relative risk (RR) 0.748, 95% confidence interval (CI), 0.605–0.924. Body mass index was associated with a greater risk of developing post-COVID-19 symptoms (RR 1.031, 95% CI, 1.016–1.047, for 1 kg/m2). A total of 378 (25.4%) people used further health services after their index COVID-19 infection, of whom 277 (73.2%) had post-COVID symptoms. Male sex was negatively associated with the use of further health services (RR 0.618, 95% CI, 0.464–0.818) whereas BMI was positively associated (RR 1.027, 95% CI, 1.009–1.046). Overall, post-COVID-19 symptoms increased the probability of using health services with RR 3.280, 95% CI, 2.540–4.262. This survey of a large number of people previously diagnosed with COVID-19 across East England shows a high prevalence of self-reported post-COVID-19 syndrome. Female sex and BMI were associated with an increased risk of post-COVID-19 syndrome and further utilisation of healthcare. Public Library of Science 2022-11-30 /pmc/articles/PMC10022108/ /pubmed/36962824 http://dx.doi.org/10.1371/journal.pgph.0001188 Text en © 2022 Debski et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Debski, Maciej
Tsampasian, Vasiliki
Haney, Shawn
Blakely, Katy
Weston, Samantha
Ntatsaki, Eleana
Lim, Mark
Madden, Susan
Perperoglou, Aris
Vassiliou, Vassilios S.
Post-COVID-19 syndrome risk factors and further use of health services in East England
title Post-COVID-19 syndrome risk factors and further use of health services in East England
title_full Post-COVID-19 syndrome risk factors and further use of health services in East England
title_fullStr Post-COVID-19 syndrome risk factors and further use of health services in East England
title_full_unstemmed Post-COVID-19 syndrome risk factors and further use of health services in East England
title_short Post-COVID-19 syndrome risk factors and further use of health services in East England
title_sort post-covid-19 syndrome risk factors and further use of health services in east england
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022108/
https://www.ncbi.nlm.nih.gov/pubmed/36962824
http://dx.doi.org/10.1371/journal.pgph.0001188
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