Circulating SARS-CoV-2(+) megakaryocytes are associated with severe viral infection in COVID-19

Several independent lines of evidence suggest that megakaryocytes are dysfunctional in severe COVID-19. Herein, we characterized peripheral circulating megakaryocytes in a large cohort of inpatients with COVID-19 and correlated the subpopulation frequencies with clinical outcomes. Using peripheral b...

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Detalles Bibliográficos
Autores principales: Fortmann, Seth D., Patton, Michael J., Frey, Blake F., Tipper, Jennifer L., Reddy, Sivani B., Vieira, Cristiano P., Hanumanthu, Vidya Sagar, Sterrett, Sarah, Floyd, Jason L., Prasad, Ram, Zucker, Jeremy D., Crouse, Andrew B., Huls, Forest, Chkheidze, Rati, Li, Peng, Erdmann, Nathaniel B., Harrod, Kevin S., Gaggar, Amit, Goepfert, Paul A., Grant, Maria B., Might, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Clinical Trials and Observations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022176/
https://www.ncbi.nlm.nih.gov/pubmed/36920790
http://dx.doi.org/10.1182/bloodadvances.2022009022

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