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Tumor cell density dependent IL-8 secretion induces the fluctuation of tregs/CD8 + T cells infiltration in hepatocellular carcinoma: one prompt for the existence of density checkpoint

BACKGROUND: Tumor cell density is a basic pathological feature of solid tumors. Chemotherapy, radiotherapy, and targeted therapy reduce tumor cell density, whereas unrestricted tumor cell proliferation promotes this feature. The impact of tumor cells on the microenvironment following changes in tumo...

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Detalles Bibliográficos
Autores principales:	Yan, Mengchao, Yao, Jia, Lin, Yan, Yan, Jun, Xie, Ye, Fu, Zongli, Zhou, Yongqiang, Wei, Jiayun, Li, Xun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022186/ https://www.ncbi.nlm.nih.gov/pubmed/36932390 http://dx.doi.org/10.1186/s12967-023-04060-3

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