Cargando…
LACE 2.0: an interactive R tool for the inference and visualization of longitudinal cancer evolution
BACKGROUND: Longitudinal single-cell sequencing experiments of patient-derived models are increasingly employed to investigate cancer evolution. In this context, robust computational methods are needed to properly exploit the mutational profiles of single cells generated via variant calling, in orde...
Autores principales: | Ascolani, Gianluca, Angaroni, Fabrizio, Maspero, Davide, Craighero, Francesco, Bhavesh, Narra Lakshmi Sai, Piazza, Rocco, Damiani, Chiara, Ramazzotti, Daniele, Antoniotti, Marco, Graudenzi, Alex |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022199/ https://www.ncbi.nlm.nih.gov/pubmed/36932333 http://dx.doi.org/10.1186/s12859-023-05221-3 |
Ejemplares similares
-
Variant calling from scRNA-seq data allows the assessment of cellular identity in patient-derived cell lines
por: Ramazzotti, Daniele, et al.
Publicado: (2022) -
VERSO: A comprehensive framework for the inference of robust phylogenies and the quantification of intra-host genomic diversity of viral samples
por: Ramazzotti, Daniele, et al.
Publicado: (2021) -
J-SPACE: a Julia package for the simulation of spatial models of cancer evolution and of sequencing experiments
por: Angaroni, Fabrizio, et al.
Publicado: (2022) -
Early detection and improved genomic surveillance of SARS-CoV-2 variants from deep sequencing data
por: Ramazzotti, Daniele, et al.
Publicado: (2022) -
Mutational signatures and heterogeneous host response revealed via large-scale characterization of SARS-CoV-2 genomic diversity
por: Graudenzi, Alex, et al.
Publicado: (2021)