SOX2 dosage sustains tumor-promoting inflammation to drive disease aggressiveness by modulating the FOSL2/IL6 axis

BACKGROUND: Inflammation is undoubtedly a hallmark of cancer development. Its maintenance within tumors and the consequences on disease aggressiveness are insufficiently understood. METHODS: Data of 27 tumor entities (about 5000 samples) were downloaded from the TCGA and GEO databases. Multi-omic an...

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Detalles Bibliográficos
Autores principales: Njouendou, Abdel Jelil, Szarvas, Tibor, Tiofack, Arnol Auvaker Zebaze, Kenfack, Rovaldo Nguims, Tonouo, Pamela Derliche, Ananga, Sidonie Noa, Bell, Esther H. M. Dina, Simo, Gustave, Hoheisel, Jörg D., Siveke, Jens T., Lueong, Smiths S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022277/
https://www.ncbi.nlm.nih.gov/pubmed/36932385
http://dx.doi.org/10.1186/s12943-023-01734-w

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