Plasma exosome miRNA-26b-3p derived from idiopathic short stature impairs longitudinal bone growth via the AKAP2/ERK1/2 axis

BACKGROUND: Currently, the etiology of idiopathic short stature (ISS) is still unclear. The poor understanding of the molecular mechanisms of ISS has largely restricted this strategy towards safe and effective clinical therapies. METHODS: The plasma exosomes of ISS children were co-cultured with nor...

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Detalles Bibliográficos
Autores principales: Liu, Xijuan, Yuan, Jinghong, Wu, Zhiwen, Zhang, Junqiu, Shen, Yunfeng, Jia, Jingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022307/
https://www.ncbi.nlm.nih.gov/pubmed/36927779
http://dx.doi.org/10.1186/s12951-023-01849-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022307/
https://www.ncbi.nlm.nih.gov/pubmed/36927779
http://dx.doi.org/10.1186/s12951-023-01849-8

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