Cargando…
Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals?
Following the approval by the FDA of two COVID-19 vaccines, which are administered in two doses three to four weeks apart, we simulate the effects of various vaccine distribution policies on the cumulative number of infections and deaths in the United States in the presence of shocks to the supply o...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022372/ https://www.ncbi.nlm.nih.gov/pubmed/36962342 http://dx.doi.org/10.1371/journal.pgph.0000498 |
_version_ | 1784908717078085632 |
---|---|
author | Ben Chaouch, Zied Lo, Andrew W. Wong, Chi Heem |
author_facet | Ben Chaouch, Zied Lo, Andrew W. Wong, Chi Heem |
author_sort | Ben Chaouch, Zied |
collection | PubMed |
description | Following the approval by the FDA of two COVID-19 vaccines, which are administered in two doses three to four weeks apart, we simulate the effects of various vaccine distribution policies on the cumulative number of infections and deaths in the United States in the presence of shocks to the supply of vaccines. Our forecasts suggest that allocating more than 50% of available doses to individuals who have not received their first dose can significantly increase the number of lives saved and significantly reduce the number of COVID-19 infections. We find that a 50% allocation saves on average 33% more lives, and prevents on average 32% more infections relative to a policy that guarantees a second dose within the recommended time frame to all individuals who have already received their first dose. In fact, in the presence of supply shocks, we find that the former policy would save on average 8, 793 lives and prevents on average 607, 100 infections while the latter policy would save on average 6, 609 lives and prevents on average 460, 743 infections. |
format | Online Article Text |
id | pubmed-10022372 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-100223722023-03-17 Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals? Ben Chaouch, Zied Lo, Andrew W. Wong, Chi Heem PLOS Glob Public Health Research Article Following the approval by the FDA of two COVID-19 vaccines, which are administered in two doses three to four weeks apart, we simulate the effects of various vaccine distribution policies on the cumulative number of infections and deaths in the United States in the presence of shocks to the supply of vaccines. Our forecasts suggest that allocating more than 50% of available doses to individuals who have not received their first dose can significantly increase the number of lives saved and significantly reduce the number of COVID-19 infections. We find that a 50% allocation saves on average 33% more lives, and prevents on average 32% more infections relative to a policy that guarantees a second dose within the recommended time frame to all individuals who have already received their first dose. In fact, in the presence of supply shocks, we find that the former policy would save on average 8, 793 lives and prevents on average 607, 100 infections while the latter policy would save on average 6, 609 lives and prevents on average 460, 743 infections. Public Library of Science 2022-07-01 /pmc/articles/PMC10022372/ /pubmed/36962342 http://dx.doi.org/10.1371/journal.pgph.0000498 Text en © 2022 Ben Chaouch et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Ben Chaouch, Zied Lo, Andrew W. Wong, Chi Heem Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals? |
title | Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals? |
title_full | Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals? |
title_fullStr | Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals? |
title_full_unstemmed | Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals? |
title_short | Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals? |
title_sort | should we allocate more covid-19 vaccine doses to non-vaccinated individuals? |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022372/ https://www.ncbi.nlm.nih.gov/pubmed/36962342 http://dx.doi.org/10.1371/journal.pgph.0000498 |
work_keys_str_mv | AT benchaouchzied shouldweallocatemorecovid19vaccinedosestononvaccinatedindividuals AT loandreww shouldweallocatemorecovid19vaccinedosestononvaccinatedindividuals AT wongchiheem shouldweallocatemorecovid19vaccinedosestononvaccinatedindividuals |