Cargando…

Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals?

Following the approval by the FDA of two COVID-19 vaccines, which are administered in two doses three to four weeks apart, we simulate the effects of various vaccine distribution policies on the cumulative number of infections and deaths in the United States in the presence of shocks to the supply o...

Descripción completa

Detalles Bibliográficos
Autores principales: Ben Chaouch, Zied, Lo, Andrew W., Wong, Chi Heem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022372/
https://www.ncbi.nlm.nih.gov/pubmed/36962342
http://dx.doi.org/10.1371/journal.pgph.0000498
_version_ 1784908717078085632
author Ben Chaouch, Zied
Lo, Andrew W.
Wong, Chi Heem
author_facet Ben Chaouch, Zied
Lo, Andrew W.
Wong, Chi Heem
author_sort Ben Chaouch, Zied
collection PubMed
description Following the approval by the FDA of two COVID-19 vaccines, which are administered in two doses three to four weeks apart, we simulate the effects of various vaccine distribution policies on the cumulative number of infections and deaths in the United States in the presence of shocks to the supply of vaccines. Our forecasts suggest that allocating more than 50% of available doses to individuals who have not received their first dose can significantly increase the number of lives saved and significantly reduce the number of COVID-19 infections. We find that a 50% allocation saves on average 33% more lives, and prevents on average 32% more infections relative to a policy that guarantees a second dose within the recommended time frame to all individuals who have already received their first dose. In fact, in the presence of supply shocks, we find that the former policy would save on average 8, 793 lives and prevents on average 607, 100 infections while the latter policy would save on average 6, 609 lives and prevents on average 460, 743 infections.
format Online
Article
Text
id pubmed-10022372
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-100223722023-03-17 Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals? Ben Chaouch, Zied Lo, Andrew W. Wong, Chi Heem PLOS Glob Public Health Research Article Following the approval by the FDA of two COVID-19 vaccines, which are administered in two doses three to four weeks apart, we simulate the effects of various vaccine distribution policies on the cumulative number of infections and deaths in the United States in the presence of shocks to the supply of vaccines. Our forecasts suggest that allocating more than 50% of available doses to individuals who have not received their first dose can significantly increase the number of lives saved and significantly reduce the number of COVID-19 infections. We find that a 50% allocation saves on average 33% more lives, and prevents on average 32% more infections relative to a policy that guarantees a second dose within the recommended time frame to all individuals who have already received their first dose. In fact, in the presence of supply shocks, we find that the former policy would save on average 8, 793 lives and prevents on average 607, 100 infections while the latter policy would save on average 6, 609 lives and prevents on average 460, 743 infections. Public Library of Science 2022-07-01 /pmc/articles/PMC10022372/ /pubmed/36962342 http://dx.doi.org/10.1371/journal.pgph.0000498 Text en © 2022 Ben Chaouch et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Ben Chaouch, Zied
Lo, Andrew W.
Wong, Chi Heem
Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals?
title Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals?
title_full Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals?
title_fullStr Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals?
title_full_unstemmed Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals?
title_short Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals?
title_sort should we allocate more covid-19 vaccine doses to non-vaccinated individuals?
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022372/
https://www.ncbi.nlm.nih.gov/pubmed/36962342
http://dx.doi.org/10.1371/journal.pgph.0000498
work_keys_str_mv AT benchaouchzied shouldweallocatemorecovid19vaccinedosestononvaccinatedindividuals
AT loandreww shouldweallocatemorecovid19vaccinedosestononvaccinatedindividuals
AT wongchiheem shouldweallocatemorecovid19vaccinedosestononvaccinatedindividuals