Cargando…

DOSIMETRIC VERIFICATION OF INTENSITY MODULATED RADIOTHERAPY (IMRT) TREATMENT PLANS FOR PROSTATE CANCER PATIENTS

Intensity modulated radiotherapy (IMRT) has become widely used as a standard radiation therapy technique for the treatment of localized prostate cancer. The transition from conformal radiotherapy (3D CRT) to a more complex IMRT technique triggered the need for more thorough verification of the accur...

Descripción completa

Detalles Bibliográficos
Autores principales: Mrčela, Iva, Gregov, Marin, Matanić, Ante, Budanec, Mirjana, Murgić, Jure, Jakšić, Blanka, Prpić, Marin, Prgomet Sečan, Angela, Frobe, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sestre Milosrdnice University Hospital and Institute of Clinical Medical Research, Vinogradska cesta c. 29 Zagreb 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022411/
https://www.ncbi.nlm.nih.gov/pubmed/36938551
http://dx.doi.org/10.20471/acc.2022.61.s3.3
_version_ 1784908725780217856
author Mrčela, Iva
Gregov, Marin
Matanić, Ante
Budanec, Mirjana
Murgić, Jure
Jakšić, Blanka
Prpić, Marin
Prgomet Sečan, Angela
Frobe, Ana
author_facet Mrčela, Iva
Gregov, Marin
Matanić, Ante
Budanec, Mirjana
Murgić, Jure
Jakšić, Blanka
Prpić, Marin
Prgomet Sečan, Angela
Frobe, Ana
author_sort Mrčela, Iva
collection PubMed
description Intensity modulated radiotherapy (IMRT) has become widely used as a standard radiation therapy technique for the treatment of localized prostate cancer. The transition from conformal radiotherapy (3D CRT) to a more complex IMRT technique triggered the need for more thorough verification of the accuracy in the dose delivery. In this work we present the clinical workflow and the results of patient specific quality assurance (PSQA) procedures for 40 prostate cancer patients who have been treated with step and shot IMRT ever since its implementation in our routine clinical practice. PSQA procedures include dosimetric verification of each treatment plan with dedicated rotational phantom and high-resolution matrix detector system Octavius 4D (PTW Freiburg) that allows three-dimensional comparison of the calculated and delivered radiation dose distribution. Our results proved the compliance with the universal tolerance limits recommended for those procedures (1), assuring the safety of the treatment and providing the possibility for the adoption of more stringent constraints in the future.
format Online
Article
Text
id pubmed-10022411
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Sestre Milosrdnice University Hospital and Institute of Clinical Medical Research, Vinogradska cesta c. 29 Zagreb
record_format MEDLINE/PubMed
spelling pubmed-100224112023-03-18 DOSIMETRIC VERIFICATION OF INTENSITY MODULATED RADIOTHERAPY (IMRT) TREATMENT PLANS FOR PROSTATE CANCER PATIENTS Mrčela, Iva Gregov, Marin Matanić, Ante Budanec, Mirjana Murgić, Jure Jakšić, Blanka Prpić, Marin Prgomet Sečan, Angela Frobe, Ana Acta Clin Croat Original Scientific Papers Intensity modulated radiotherapy (IMRT) has become widely used as a standard radiation therapy technique for the treatment of localized prostate cancer. The transition from conformal radiotherapy (3D CRT) to a more complex IMRT technique triggered the need for more thorough verification of the accuracy in the dose delivery. In this work we present the clinical workflow and the results of patient specific quality assurance (PSQA) procedures for 40 prostate cancer patients who have been treated with step and shot IMRT ever since its implementation in our routine clinical practice. PSQA procedures include dosimetric verification of each treatment plan with dedicated rotational phantom and high-resolution matrix detector system Octavius 4D (PTW Freiburg) that allows three-dimensional comparison of the calculated and delivered radiation dose distribution. Our results proved the compliance with the universal tolerance limits recommended for those procedures (1), assuring the safety of the treatment and providing the possibility for the adoption of more stringent constraints in the future. Sestre Milosrdnice University Hospital and Institute of Clinical Medical Research, Vinogradska cesta c. 29 Zagreb 2022-10 /pmc/articles/PMC10022411/ /pubmed/36938551 http://dx.doi.org/10.20471/acc.2022.61.s3.3 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND) 4.0 License.
spellingShingle Original Scientific Papers
Mrčela, Iva
Gregov, Marin
Matanić, Ante
Budanec, Mirjana
Murgić, Jure
Jakšić, Blanka
Prpić, Marin
Prgomet Sečan, Angela
Frobe, Ana
DOSIMETRIC VERIFICATION OF INTENSITY MODULATED RADIOTHERAPY (IMRT) TREATMENT PLANS FOR PROSTATE CANCER PATIENTS
title DOSIMETRIC VERIFICATION OF INTENSITY MODULATED RADIOTHERAPY (IMRT) TREATMENT PLANS FOR PROSTATE CANCER PATIENTS
title_full DOSIMETRIC VERIFICATION OF INTENSITY MODULATED RADIOTHERAPY (IMRT) TREATMENT PLANS FOR PROSTATE CANCER PATIENTS
title_fullStr DOSIMETRIC VERIFICATION OF INTENSITY MODULATED RADIOTHERAPY (IMRT) TREATMENT PLANS FOR PROSTATE CANCER PATIENTS
title_full_unstemmed DOSIMETRIC VERIFICATION OF INTENSITY MODULATED RADIOTHERAPY (IMRT) TREATMENT PLANS FOR PROSTATE CANCER PATIENTS
title_short DOSIMETRIC VERIFICATION OF INTENSITY MODULATED RADIOTHERAPY (IMRT) TREATMENT PLANS FOR PROSTATE CANCER PATIENTS
title_sort dosimetric verification of intensity modulated radiotherapy (imrt) treatment plans for prostate cancer patients
topic Original Scientific Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022411/
https://www.ncbi.nlm.nih.gov/pubmed/36938551
http://dx.doi.org/10.20471/acc.2022.61.s3.3
work_keys_str_mv AT mrcelaiva dosimetricverificationofintensitymodulatedradiotherapyimrttreatmentplansforprostatecancerpatients
AT gregovmarin dosimetricverificationofintensitymodulatedradiotherapyimrttreatmentplansforprostatecancerpatients
AT matanicante dosimetricverificationofintensitymodulatedradiotherapyimrttreatmentplansforprostatecancerpatients
AT budanecmirjana dosimetricverificationofintensitymodulatedradiotherapyimrttreatmentplansforprostatecancerpatients
AT murgicjure dosimetricverificationofintensitymodulatedradiotherapyimrttreatmentplansforprostatecancerpatients
AT jaksicblanka dosimetricverificationofintensitymodulatedradiotherapyimrttreatmentplansforprostatecancerpatients
AT prpicmarin dosimetricverificationofintensitymodulatedradiotherapyimrttreatmentplansforprostatecancerpatients
AT prgometsecanangela dosimetricverificationofintensitymodulatedradiotherapyimrttreatmentplansforprostatecancerpatients
AT frobeana dosimetricverificationofintensitymodulatedradiotherapyimrttreatmentplansforprostatecancerpatients