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The SIX1/LDHA Axis Promotes Lactate Accumulation and Leads to NK Cell Dysfunction in Pancreatic Cancer

BACKGROUND: Pancreatic cancer (PC) is a malignant cancer with poor prognosis and high mortality rate. Sine oculis homeobox homolog 1 (SIX1) participates in the development of many cancers. However, the function of SIX1 in PC is not fully understood. METHODS: SIX1 expression was determined using immu...

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Detalles Bibliográficos
Autores principales:	Ge, Wanli, Meng, Lingdong, Cao, Shouji, Hou, Chaoqun, Zhu, Xiaole, Huang, Dongya, Li, Qiang, Peng, Yunpeng, Jiang, Kuirong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022590/ https://www.ncbi.nlm.nih.gov/pubmed/36937004 http://dx.doi.org/10.1155/2023/6891636

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