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Logistic Regression With Machine Learning Sheds Light on the Problematic Sexual Behavior Phenotype

There has been a longstanding debate about whether the mechanisms involved in problematic sexual behavior (PSB) are similar to those observed in addictive disorders, or related to impulse control or to compulsivity. The aim of this report was to contribute to this debate by investigating the associa...

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Autores principales: Jiang, Shui, Wallace, Keanna, Yang, Esther, Roper, Leslie, Aryal, Garima, Lee, Dawon, Lodhi, Rohit J., Arnau, Randolph, Isenberg, Rick, Green, Bradley, Wishart, David, Aitchison, Katherine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022667/
https://www.ncbi.nlm.nih.gov/pubmed/36193910
http://dx.doi.org/10.1097/ADM.0000000000001078
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author Jiang, Shui
Wallace, Keanna
Yang, Esther
Roper, Leslie
Aryal, Garima
Lee, Dawon
Lodhi, Rohit J.
Arnau, Randolph
Isenberg, Rick
Green, Bradley
Wishart, David
Aitchison, Katherine J.
author_facet Jiang, Shui
Wallace, Keanna
Yang, Esther
Roper, Leslie
Aryal, Garima
Lee, Dawon
Lodhi, Rohit J.
Arnau, Randolph
Isenberg, Rick
Green, Bradley
Wishart, David
Aitchison, Katherine J.
author_sort Jiang, Shui
collection PubMed
description There has been a longstanding debate about whether the mechanisms involved in problematic sexual behavior (PSB) are similar to those observed in addictive disorders, or related to impulse control or to compulsivity. The aim of this report was to contribute to this debate by investigating the association between PSB, addictive disorders (internet addiction, compulsive buying), measures associated with the construct known as reward deficiency (RDS), and obsessive-compulsive disorder (OCD). METHODS: A Canadian university Office of the Registrar invited 68,846 eligible students and postdoctoral fellows. Of 4710 expressing interest in participating, 3359 completed online questionnaires, and 1801 completed the Mini-International Neuropsychiatric Interview. PSB was measured by combining those screening positive (score at least 6) on the Sexual Addiction Screening Test—Revised Core with those self-reporting PSB. Current mental health condition(s) and childhood trauma were measured by self-report. OCD was assessed by a combination of self-report and Mini-International Neuropsychiatric Interview data. RESULTS: Of 3341 participants, 407 (12.18%) screened positive on the Sexual Addiction Screening Test—Revised Core. On logistic regression, OCD, attention deficit, internet addiction, a family history of PSB, childhood trauma, compulsive buying, and male gender were associated with PSB. On multiple correspondence analysis, OCD appeared to cluster separately from the other measures, and the pattern of data differed by gender. CONCLUSIONS: In our sample, factors that have previously been associated with RDS and OCD are both associated with increased odds of PSB. The factors associated with RDS appear to contribute to a separate data cluster from OCD and to lie closer to PSB.
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spelling pubmed-100226672023-03-18 Logistic Regression With Machine Learning Sheds Light on the Problematic Sexual Behavior Phenotype Jiang, Shui Wallace, Keanna Yang, Esther Roper, Leslie Aryal, Garima Lee, Dawon Lodhi, Rohit J. Arnau, Randolph Isenberg, Rick Green, Bradley Wishart, David Aitchison, Katherine J. J Addict Med Original Research There has been a longstanding debate about whether the mechanisms involved in problematic sexual behavior (PSB) are similar to those observed in addictive disorders, or related to impulse control or to compulsivity. The aim of this report was to contribute to this debate by investigating the association between PSB, addictive disorders (internet addiction, compulsive buying), measures associated with the construct known as reward deficiency (RDS), and obsessive-compulsive disorder (OCD). METHODS: A Canadian university Office of the Registrar invited 68,846 eligible students and postdoctoral fellows. Of 4710 expressing interest in participating, 3359 completed online questionnaires, and 1801 completed the Mini-International Neuropsychiatric Interview. PSB was measured by combining those screening positive (score at least 6) on the Sexual Addiction Screening Test—Revised Core with those self-reporting PSB. Current mental health condition(s) and childhood trauma were measured by self-report. OCD was assessed by a combination of self-report and Mini-International Neuropsychiatric Interview data. RESULTS: Of 3341 participants, 407 (12.18%) screened positive on the Sexual Addiction Screening Test—Revised Core. On logistic regression, OCD, attention deficit, internet addiction, a family history of PSB, childhood trauma, compulsive buying, and male gender were associated with PSB. On multiple correspondence analysis, OCD appeared to cluster separately from the other measures, and the pattern of data differed by gender. CONCLUSIONS: In our sample, factors that have previously been associated with RDS and OCD are both associated with increased odds of PSB. The factors associated with RDS appear to contribute to a separate data cluster from OCD and to lie closer to PSB. Lippincott Williams & Wilkins 2023 2022-10-02 /pmc/articles/PMC10022667/ /pubmed/36193910 http://dx.doi.org/10.1097/ADM.0000000000001078 Text en Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Society of Addiction Medicine. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Original Research
Jiang, Shui
Wallace, Keanna
Yang, Esther
Roper, Leslie
Aryal, Garima
Lee, Dawon
Lodhi, Rohit J.
Arnau, Randolph
Isenberg, Rick
Green, Bradley
Wishart, David
Aitchison, Katherine J.
Logistic Regression With Machine Learning Sheds Light on the Problematic Sexual Behavior Phenotype
title Logistic Regression With Machine Learning Sheds Light on the Problematic Sexual Behavior Phenotype
title_full Logistic Regression With Machine Learning Sheds Light on the Problematic Sexual Behavior Phenotype
title_fullStr Logistic Regression With Machine Learning Sheds Light on the Problematic Sexual Behavior Phenotype
title_full_unstemmed Logistic Regression With Machine Learning Sheds Light on the Problematic Sexual Behavior Phenotype
title_short Logistic Regression With Machine Learning Sheds Light on the Problematic Sexual Behavior Phenotype
title_sort logistic regression with machine learning sheds light on the problematic sexual behavior phenotype
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022667/
https://www.ncbi.nlm.nih.gov/pubmed/36193910
http://dx.doi.org/10.1097/ADM.0000000000001078
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