SeDeM expert system with I-optimal mixture design for oral multiparticulate drug delivery: An encapsulated floating minitablets of loxoprofen Na and its in silico physiologically based pharmacokinetic modeling

Introduction: A SeDeM expert tool-driven I-optimal mixture design has been used to develop a directly compressible multiparticulate based extended release minitablets for gastro-retentive drug delivery systems using loxoprofen sodium as a model drug. Methods: Powder blends were subjected to stress d...

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Detalles Bibliográficos
Autores principales: Rauf-ur-Rehman, Shoaib, Muhammad Harris, Ahmed, Farrukh Rafiq, Yousuf, Rabia Ismail, Siddiqui, Fahad, Saleem, Muhammad Talha, Qazi, Faaiza, Khan, Momina Zarish, Irshad, Asma, Bashir, Lubna, Naz, Shazia, Farooq, Muhammad, Mahmood, Zafar Alam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022826/
https://www.ncbi.nlm.nih.gov/pubmed/36937845
http://dx.doi.org/10.3389/fphar.2023.1066018

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