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Kindlin-1 regulates IL-6 secretion and modulates the immune environment in breast cancer models
The adhesion protein Kindlin-1 is over-expressed in breast cancer where it is associated with metastasis-free survival; however, the mechanisms involved are poorly understood. Here, we report that Kindlin-1 promotes anti-tumor immune evasion in mouse models of breast cancer. Deletion of Kindlin-1 in...
Autores principales: | Webb, Emily R, Dodd, Georgia L, Noskova, Michaela, Bullock, Esme, Muir, Morwenna, Frame, Margaret C, Serrels, Alan, Brunton, Valerie G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023156/ https://www.ncbi.nlm.nih.gov/pubmed/36883731 http://dx.doi.org/10.7554/eLife.85739 |
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