Identifying promising druggable binding sites and their flexibility to target the receptor-binding domain of SARS-CoV-2 spike protein

The spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is crucial for viral infection. The interaction of its receptor-binding domain (RBD) with the human angiotensin-converting enzyme 2 (ACE2) protein is required for the virus to enter the host cell. We identified RBD bin...

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Detalles Bibliográficos
Autores principales: Ghoula, M., Naceri, S., Sitruk, S., Flatters, D., Moroy, G., Camproux, A.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023212/
https://www.ncbi.nlm.nih.gov/pubmed/36998674
http://dx.doi.org/10.1016/j.csbj.2023.03.029

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