ATM suppresses c-Myc overexpression in the mammary epithelium in response to estrogen

ATM gene mutation carriers are predisposed to estrogen-receptor-positive breast cancer (BC). ATM prevents BC oncogenesis by activating p53 in every cell; however, much remains unknown about tissue-specific oncogenesis after ATM loss. Here, we report that ATM controls the early transcriptional respon...

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Detalles Bibliográficos
Autores principales: Najnin, Rifat Ara, Al Mahmud, Md Rasel, Rahman, Md Maminur, Takeda, Shunichi, Sasanuma, Hiroyuki, Tanaka, Hisashi, Murakawa, Yasuhiro, Shimizu, Naoto, Akter, Salma, Takagi, Masatoshi, Sunada, Takuro, Akamatsu, Shusuke, He, Gang, Itou, Junji, Toi, Masakazu, Miyaji, Mary, Tsutsui, Kimiko M., Keeney, Scott, Yamada, Shintaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023214/
https://www.ncbi.nlm.nih.gov/pubmed/36640339
http://dx.doi.org/10.1016/j.celrep.2022.111909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023214/
https://www.ncbi.nlm.nih.gov/pubmed/36640339
http://dx.doi.org/10.1016/j.celrep.2022.111909

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