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The role of quick Sepsis-related Organ Failure Assessment score as simple scoring system to predict Fournier gangrene mortality and the correlation with Fournier's Gangrene Severity Index: Analysis of 69 patients

OBJECTIVE: Fournier's gangrene is a rare but life-threatening infection disease with high mortality rate. The quick Sepsis-related Organ Failure Assessment (qSOFA) is a new and simpler scoring system that may identify patients with suspected infection who are at greater risk for a poor outcome....

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Autores principales: Noegroho, Bambang S., Adi, Kuncoro, Mustafa, Akhmad, Haq, Rais Syaeful, Wijayanti, Zola, Liarto, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Second Military Medical University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023526/
https://www.ncbi.nlm.nih.gov/pubmed/36942123
http://dx.doi.org/10.1016/j.ajur.2021.11.003
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author Noegroho, Bambang S.
Adi, Kuncoro
Mustafa, Akhmad
Haq, Rais Syaeful
Wijayanti, Zola
Liarto, Jason
author_facet Noegroho, Bambang S.
Adi, Kuncoro
Mustafa, Akhmad
Haq, Rais Syaeful
Wijayanti, Zola
Liarto, Jason
author_sort Noegroho, Bambang S.
collection PubMed
description OBJECTIVE: Fournier's gangrene is a rare but life-threatening infection disease with high mortality rate. The quick Sepsis-related Organ Failure Assessment (qSOFA) is a new and simpler scoring system that may identify patients with suspected infection who are at greater risk for a poor outcome. The purpose of this study was to find out role of qSOFA in determining prognosis of Fournier's gangrene patients. METHODS: This study is a case control with retrospective review of Fournier's gangrene patients treated at Hasan Sadikin Hospital from January 2013 to December 2017 who met inclusion criteria. Participants were divided into two groups according to qSOFA score as high qSOFA (2–3) and low qSOFA (0–1). RESULTS: From 69 patients, the mortality rate was 24.6%. The sensitivity of qSOFA score to predict mortality was 88.2%; the specificity was 94.2%; positive predictive value was 83.3%; negative predictive value was 96.1%; positive likelihood ratio was 15.2; negative likelihood ratio was 0.12; and the area under the receiver operating characteristic curve of qSOFA was 94.2%. There was significant association between qSOFA scale and mortality with p-value of 0.0001. The qSOFA score has strong positive correlation with Fournier's Gangrene Severity Index (p<0.0001, r=0.704). CONCLUSION: qSOFA scoring system has a high prognostic value and can be used to determine prognosis of Fournier's gangrene patients.
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spelling pubmed-100235262023-03-19 The role of quick Sepsis-related Organ Failure Assessment score as simple scoring system to predict Fournier gangrene mortality and the correlation with Fournier's Gangrene Severity Index: Analysis of 69 patients Noegroho, Bambang S. Adi, Kuncoro Mustafa, Akhmad Haq, Rais Syaeful Wijayanti, Zola Liarto, Jason Asian J Urol Original Article OBJECTIVE: Fournier's gangrene is a rare but life-threatening infection disease with high mortality rate. The quick Sepsis-related Organ Failure Assessment (qSOFA) is a new and simpler scoring system that may identify patients with suspected infection who are at greater risk for a poor outcome. The purpose of this study was to find out role of qSOFA in determining prognosis of Fournier's gangrene patients. METHODS: This study is a case control with retrospective review of Fournier's gangrene patients treated at Hasan Sadikin Hospital from January 2013 to December 2017 who met inclusion criteria. Participants were divided into two groups according to qSOFA score as high qSOFA (2–3) and low qSOFA (0–1). RESULTS: From 69 patients, the mortality rate was 24.6%. The sensitivity of qSOFA score to predict mortality was 88.2%; the specificity was 94.2%; positive predictive value was 83.3%; negative predictive value was 96.1%; positive likelihood ratio was 15.2; negative likelihood ratio was 0.12; and the area under the receiver operating characteristic curve of qSOFA was 94.2%. There was significant association between qSOFA scale and mortality with p-value of 0.0001. The qSOFA score has strong positive correlation with Fournier's Gangrene Severity Index (p<0.0001, r=0.704). CONCLUSION: qSOFA scoring system has a high prognostic value and can be used to determine prognosis of Fournier's gangrene patients. Second Military Medical University 2023-04 2021-11-19 /pmc/articles/PMC10023526/ /pubmed/36942123 http://dx.doi.org/10.1016/j.ajur.2021.11.003 Text en © 2022 Editorial Office of Asian Journal of Urology. Production and hosting by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Noegroho, Bambang S.
Adi, Kuncoro
Mustafa, Akhmad
Haq, Rais Syaeful
Wijayanti, Zola
Liarto, Jason
The role of quick Sepsis-related Organ Failure Assessment score as simple scoring system to predict Fournier gangrene mortality and the correlation with Fournier's Gangrene Severity Index: Analysis of 69 patients
title The role of quick Sepsis-related Organ Failure Assessment score as simple scoring system to predict Fournier gangrene mortality and the correlation with Fournier's Gangrene Severity Index: Analysis of 69 patients
title_full The role of quick Sepsis-related Organ Failure Assessment score as simple scoring system to predict Fournier gangrene mortality and the correlation with Fournier's Gangrene Severity Index: Analysis of 69 patients
title_fullStr The role of quick Sepsis-related Organ Failure Assessment score as simple scoring system to predict Fournier gangrene mortality and the correlation with Fournier's Gangrene Severity Index: Analysis of 69 patients
title_full_unstemmed The role of quick Sepsis-related Organ Failure Assessment score as simple scoring system to predict Fournier gangrene mortality and the correlation with Fournier's Gangrene Severity Index: Analysis of 69 patients
title_short The role of quick Sepsis-related Organ Failure Assessment score as simple scoring system to predict Fournier gangrene mortality and the correlation with Fournier's Gangrene Severity Index: Analysis of 69 patients
title_sort role of quick sepsis-related organ failure assessment score as simple scoring system to predict fournier gangrene mortality and the correlation with fournier's gangrene severity index: analysis of 69 patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023526/
https://www.ncbi.nlm.nih.gov/pubmed/36942123
http://dx.doi.org/10.1016/j.ajur.2021.11.003
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