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Radiofrequency ablation for renal tumours: A retrospective study from a tertiary centre

OBJECTIVE: This study aimed to evaluate the safety and efficacy outcomes of percutaneous radiofrequency ablation (RFA) for localised renal cell carcinoma (RCC) in a tertiary hospital patient who remained unfit for surgical intervention. METHODS: We retrospectively analysed survival outcomes for pati...

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Detalles Bibliográficos
Autores principales: Al-Zubaidi, Mohammed, Lotter, Kennia, Marshall, Martin, Lozinskiy, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Second Military Medical University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023533/
https://www.ncbi.nlm.nih.gov/pubmed/36942114
http://dx.doi.org/10.1016/j.ajur.2021.10.003
Descripción
Sumario:OBJECTIVE: This study aimed to evaluate the safety and efficacy outcomes of percutaneous radiofrequency ablation (RFA) for localised renal cell carcinoma (RCC) in a tertiary hospital patient who remained unfit for surgical intervention. METHODS: We retrospectively analysed survival outcomes for patients with biopsy proven RCC treated by RFA at Royal Perth Hospital between September 2009 and May 2018. Complication data were gathered for all patients that underwent renal RFA along with 2- and 5-year recurrence-free survival (RFS) rate and compared the outcomes with data from previous studies. RESULTS: A total of 69 patients (73 procedures) were eligible for the study, and those patients had biopsy-proven RCC with a minimum of 2-year follow-up. The complication rate was 8.2% (6/73) and local recurrence rate 9.6% (7/73). Two-year RFS is 95.7% and 5-year RFS is 78.8% on a median 3.82-year follow-up (interquartile range 1.90–5.75 years). CONCLUSION: RFA performed at our centre was found to be safe and effective with low complication rates and durable RFS in line with expectations from existing research. Our study demonstrated that RFA is an alternative modality of treatment for small renal tumours in patients unfit for surgical approach.