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Radiofrequency ablation for renal tumours: A retrospective study from a tertiary centre

OBJECTIVE: This study aimed to evaluate the safety and efficacy outcomes of percutaneous radiofrequency ablation (RFA) for localised renal cell carcinoma (RCC) in a tertiary hospital patient who remained unfit for surgical intervention. METHODS: We retrospectively analysed survival outcomes for pati...

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Autores principales: Al-Zubaidi, Mohammed, Lotter, Kennia, Marshall, Martin, Lozinskiy, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Second Military Medical University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023533/
https://www.ncbi.nlm.nih.gov/pubmed/36942114
http://dx.doi.org/10.1016/j.ajur.2021.10.003
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author Al-Zubaidi, Mohammed
Lotter, Kennia
Marshall, Martin
Lozinskiy, Mikhail
author_facet Al-Zubaidi, Mohammed
Lotter, Kennia
Marshall, Martin
Lozinskiy, Mikhail
author_sort Al-Zubaidi, Mohammed
collection PubMed
description OBJECTIVE: This study aimed to evaluate the safety and efficacy outcomes of percutaneous radiofrequency ablation (RFA) for localised renal cell carcinoma (RCC) in a tertiary hospital patient who remained unfit for surgical intervention. METHODS: We retrospectively analysed survival outcomes for patients with biopsy proven RCC treated by RFA at Royal Perth Hospital between September 2009 and May 2018. Complication data were gathered for all patients that underwent renal RFA along with 2- and 5-year recurrence-free survival (RFS) rate and compared the outcomes with data from previous studies. RESULTS: A total of 69 patients (73 procedures) were eligible for the study, and those patients had biopsy-proven RCC with a minimum of 2-year follow-up. The complication rate was 8.2% (6/73) and local recurrence rate 9.6% (7/73). Two-year RFS is 95.7% and 5-year RFS is 78.8% on a median 3.82-year follow-up (interquartile range 1.90–5.75 years). CONCLUSION: RFA performed at our centre was found to be safe and effective with low complication rates and durable RFS in line with expectations from existing research. Our study demonstrated that RFA is an alternative modality of treatment for small renal tumours in patients unfit for surgical approach.
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spelling pubmed-100235332023-03-19 Radiofrequency ablation for renal tumours: A retrospective study from a tertiary centre Al-Zubaidi, Mohammed Lotter, Kennia Marshall, Martin Lozinskiy, Mikhail Asian J Urol Original Article OBJECTIVE: This study aimed to evaluate the safety and efficacy outcomes of percutaneous radiofrequency ablation (RFA) for localised renal cell carcinoma (RCC) in a tertiary hospital patient who remained unfit for surgical intervention. METHODS: We retrospectively analysed survival outcomes for patients with biopsy proven RCC treated by RFA at Royal Perth Hospital between September 2009 and May 2018. Complication data were gathered for all patients that underwent renal RFA along with 2- and 5-year recurrence-free survival (RFS) rate and compared the outcomes with data from previous studies. RESULTS: A total of 69 patients (73 procedures) were eligible for the study, and those patients had biopsy-proven RCC with a minimum of 2-year follow-up. The complication rate was 8.2% (6/73) and local recurrence rate 9.6% (7/73). Two-year RFS is 95.7% and 5-year RFS is 78.8% on a median 3.82-year follow-up (interquartile range 1.90–5.75 years). CONCLUSION: RFA performed at our centre was found to be safe and effective with low complication rates and durable RFS in line with expectations from existing research. Our study demonstrated that RFA is an alternative modality of treatment for small renal tumours in patients unfit for surgical approach. Second Military Medical University 2023-04 2021-11-06 /pmc/articles/PMC10023533/ /pubmed/36942114 http://dx.doi.org/10.1016/j.ajur.2021.10.003 Text en © 2022 Editorial Office of Asian Journal of Urology. Production and hosting by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Al-Zubaidi, Mohammed
Lotter, Kennia
Marshall, Martin
Lozinskiy, Mikhail
Radiofrequency ablation for renal tumours: A retrospective study from a tertiary centre
title Radiofrequency ablation for renal tumours: A retrospective study from a tertiary centre
title_full Radiofrequency ablation for renal tumours: A retrospective study from a tertiary centre
title_fullStr Radiofrequency ablation for renal tumours: A retrospective study from a tertiary centre
title_full_unstemmed Radiofrequency ablation for renal tumours: A retrospective study from a tertiary centre
title_short Radiofrequency ablation for renal tumours: A retrospective study from a tertiary centre
title_sort radiofrequency ablation for renal tumours: a retrospective study from a tertiary centre
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023533/
https://www.ncbi.nlm.nih.gov/pubmed/36942114
http://dx.doi.org/10.1016/j.ajur.2021.10.003
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AT lozinskiymikhail radiofrequencyablationforrenaltumoursaretrospectivestudyfromatertiarycentre