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DIAPH1 mediates progression of atherosclerosis and regulates hepatic lipid metabolism in mice

Atherosclerosis evolves through dysregulated lipid metabolism interwoven with exaggerated inflammation. Previous work implicating the receptor for advanced glycation end products (RAGE) in atherosclerosis prompted us to explore if Diaphanous 1 (DIAPH1), which binds to the RAGE cytoplasmic domain and...

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Detalles Bibliográficos
Autores principales: Senatus, Laura, Egaña-Gorroño, Lander, López-Díez, Raquel, Bergaya, Sonia, Aranda, Juan Francisco, Amengual, Jaume, Arivazhagan, Lakshmi, Manigrasso, Michaele B., Yepuri, Gautham, Nimma, Ramesh, Mangar, Kaamashri N., Bernadin, Rollanda, Zhou, Boyan, Gugger, Paul F., Li, Huilin, Friedman, Richard A., Theise, Neil D., Shekhtman, Alexander, Fisher, Edward A., Ramasamy, Ravichandran, Schmidt, Ann Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023694/
https://www.ncbi.nlm.nih.gov/pubmed/36932214
http://dx.doi.org/10.1038/s42003-023-04643-2