The tetraspanin CD53 protects stressed hematopoietic stem cells via promotion of DREAM complex–mediated quiescence

The hematopoietic stem cell (HSC) cycle responds to inflammatory and other proliferative stressors; however, these cells must quickly return to quiescence to avoid exhaustion and maintain their functional integrity. The mechanisms that regulate this return to quiescence are not well understood. Here...

Descripción completa

Detalles Bibliográficos
Autores principales: Greenberg, Zev J., Paracatu, Luana Chiquetto, Monlish, Darlene A., Dong, Qian, Rettig, Michael, Roundy, Nate, Gaballa, Rofaida, Li, Weikai, Yang, Wei, Luke, Cliff J., Schuettpelz, Laura G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Hematopoiesis and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023726/
https://www.ncbi.nlm.nih.gov/pubmed/36542833
http://dx.doi.org/10.1182/blood.2022016929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023726/
https://www.ncbi.nlm.nih.gov/pubmed/36542833
http://dx.doi.org/10.1182/blood.2022016929

Ejemplares similares