Precise programming of multigene expression stoichiometry in mammalian cells by a modular and programmable transcriptional system

Context-dependency of mammalian transcriptional elements has hindered the quantitative investigation of multigene expression stoichiometry and its biological functions. Here, we describe a host- and local DNA context-independent transcription system to gradually fine-tune single and multiple gene ex...

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Detalles Bibliográficos
Autores principales: Qin, Chenrui, Xiang, Yanhui, Liu, Jie, Zhang, Ruilin, Liu, Ziming, Li, Tingting, Sun, Zhi, Ouyang, Xiaoyi, Zong, Yeqing, Zhang, Haoqian M., Ouyang, Qi, Qian, Long, Lou, Chunbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023750/
https://www.ncbi.nlm.nih.gov/pubmed/36932109
http://dx.doi.org/10.1038/s41467-023-37244-y

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