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Transcription factor SOX15 regulates stem cell pluripotency and promotes neural fate during differentiation by activating the neurogenic gene Hes5

SOX2 and SOX15 are Sox family transcription factors enriched in embryonic stem cells (ESCs). The role of SOX2 in activating gene expression programs essential for stem cell self-renewal and acquisition of pluripotency during somatic cell reprogramming is well-documented. However, the contribution of...

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Detalles Bibliográficos
Autores principales: Choi, Eun-Bee, Vodnala, Munender, Saini, Prince, Anugula, Sharath, Zerbato, Madeleine, Ho, Jaclyn J., Wang, Jianing, Ho Sui, Shannan J., Yoon, Joon, Roels, Marielle, Inouye, Carla, Fong, Yick W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023989/
https://www.ncbi.nlm.nih.gov/pubmed/36764520
http://dx.doi.org/10.1016/j.jbc.2023.102996