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Antitumor effect of neoantigen-reactive T cells combined with PD1 inhibitor therapy in mouse lung cancer

PURPOSE: Neoantigens produced from mutations in tumors are important targets of T-cell-based immunotherapy and immune checkpoint blockade has been approved for treating multiple solid tumors. We investigated the potential benefit of adoptive neoantigen-reactive T (NRT) cells in combination with prog...

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Detalles Bibliográficos
Autores principales: Qin, Huan, Hu, Haiyan, Liao, Ximing, Zhao, Pei, He, Wenjuan, Su, Xiaoping, Sun, Jiaxing, Li, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024025/
https://www.ncbi.nlm.nih.gov/pubmed/36933035
http://dx.doi.org/10.1007/s00432-023-04683-5