The effectiveness of tyrosine kinase inhibitor for chronic myeloid leukemia in tuberous sclerosis. A case report and review of literature

The relationship between chronic myelogenous leukemia (CML) and tuberous sclerosis (TS) is unusual and uncommon. Here, we report a 24‐year‐old woman diagnosed with TS and later identified with CML, as the second case reported with such coexistence, treated with Nilotinib. This article proposes a hyp...

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Autores principales: Al‐Abdulmalek, Abdulrahman, Al‐Suliman, Reem, Abu‐Tineh, Mohammad, Ali, Mostafa, Yassin, Mohamed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024035/
https://www.ncbi.nlm.nih.gov/pubmed/36941833
http://dx.doi.org/10.1002/ccr3.7087
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author Al‐Abdulmalek, Abdulrahman
Al‐Suliman, Reem
Abu‐Tineh, Mohammad
Ali, Mostafa
Yassin, Mohamed A.
author_facet Al‐Abdulmalek, Abdulrahman
Al‐Suliman, Reem
Abu‐Tineh, Mohammad
Ali, Mostafa
Yassin, Mohamed A.
author_sort Al‐Abdulmalek, Abdulrahman
collection PubMed
description The relationship between chronic myelogenous leukemia (CML) and tuberous sclerosis (TS) is unusual and uncommon. Here, we report a 24‐year‐old woman diagnosed with TS and later identified with CML, as the second case reported with such coexistence, treated with Nilotinib. This article proposes a hypothesis to explain the association. Therefore, we propose Nilotinib for the treatment of patients with such coexisting diseases. Further studies are warranted to reveal the dynamics between these conditions.
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spelling pubmed-100240352023-03-19 The effectiveness of tyrosine kinase inhibitor for chronic myeloid leukemia in tuberous sclerosis. A case report and review of literature Al‐Abdulmalek, Abdulrahman Al‐Suliman, Reem Abu‐Tineh, Mohammad Ali, Mostafa Yassin, Mohamed A. Clin Case Rep Case Report The relationship between chronic myelogenous leukemia (CML) and tuberous sclerosis (TS) is unusual and uncommon. Here, we report a 24‐year‐old woman diagnosed with TS and later identified with CML, as the second case reported with such coexistence, treated with Nilotinib. This article proposes a hypothesis to explain the association. Therefore, we propose Nilotinib for the treatment of patients with such coexisting diseases. Further studies are warranted to reveal the dynamics between these conditions. John Wiley and Sons Inc. 2023-03-17 /pmc/articles/PMC10024035/ /pubmed/36941833 http://dx.doi.org/10.1002/ccr3.7087 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Report
Al‐Abdulmalek, Abdulrahman
Al‐Suliman, Reem
Abu‐Tineh, Mohammad
Ali, Mostafa
Yassin, Mohamed A.
The effectiveness of tyrosine kinase inhibitor for chronic myeloid leukemia in tuberous sclerosis. A case report and review of literature
title The effectiveness of tyrosine kinase inhibitor for chronic myeloid leukemia in tuberous sclerosis. A case report and review of literature
title_full The effectiveness of tyrosine kinase inhibitor for chronic myeloid leukemia in tuberous sclerosis. A case report and review of literature
title_fullStr The effectiveness of tyrosine kinase inhibitor for chronic myeloid leukemia in tuberous sclerosis. A case report and review of literature
title_full_unstemmed The effectiveness of tyrosine kinase inhibitor for chronic myeloid leukemia in tuberous sclerosis. A case report and review of literature
title_short The effectiveness of tyrosine kinase inhibitor for chronic myeloid leukemia in tuberous sclerosis. A case report and review of literature
title_sort effectiveness of tyrosine kinase inhibitor for chronic myeloid leukemia in tuberous sclerosis. a case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024035/
https://www.ncbi.nlm.nih.gov/pubmed/36941833
http://dx.doi.org/10.1002/ccr3.7087
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