Proteomic analysis of brain metastatic lung adenocarcinoma reveals intertumoral heterogeneity and specific alterations associated with the timing of brain metastases

BACKGROUND: Brain metastases are associated with considerable negative effects on patients’ outcome in lung adenocarcinoma (LADC). Here, we investigated the proteomic landscape of primary LADCs and their corresponding brain metastases. MATERIALS AND METHODS: Proteomic profiling was conducted on 20 s...

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Detalles Bibliográficos
Autores principales: Woldmar, N., Schwendenwein, A., Kuras, M., Szeitz, B., Boettiger, K., Tisza, A., László, V., Reiniger, L., Bagó, A.G., Szállási, Z., Moldvay, J., Szász, A.M., Malm, J., Horvatovich, P., Pizzatti, L., Domont, G.B., Rényi-Vámos, F., Hoetzenecker, K., Hoda, M.A., Marko-Varga, G., Schelch, K., Megyesfalvi, Z., Rezeli, M., Döme, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024110/
https://www.ncbi.nlm.nih.gov/pubmed/36527824
http://dx.doi.org/10.1016/j.esmoop.2022.100741

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