Multi-omics analysis uncovers tumor ecosystem dynamics during neoadjuvant toripalimab plus nab-paclitaxel and S-1 for esophageal squamous cell carcinoma: a single-center, open-label, single-arm phase 2 trial

BACKGROUND: Immune checkpoint inhibitors combined with chemotherapy as a neoadjuvant therapy have been applied to the treatment of esophageal squamous cell carcinoma (ESCC). However, the optimal regimen needs to be further explored, particularly for older patients, and the mechanisms by which the im...

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Detalles Bibliográficos
Autores principales: Zhang, Guoqing, Yuan, Jing, Pan, Chaohu, Xu, Qing, Cui, Xiaoli, Zhang, Jing, Liu, Minglu, Song, Zhigang, Wu, Liangliang, Wu, Dongfang, Luo, Haitao, Hu, Yi, Jiao, Shunchang, Yang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024111/
https://www.ncbi.nlm.nih.gov/pubmed/36921563
http://dx.doi.org/10.1016/j.ebiom.2023.104515

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