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The complex genetic architecture of Alzheimer's disease: novel insights and future directions

BACKGROUND: Alzheimer's disease (AD) is a complex multifactorial neurodegenerative disorder and the most common form of dementia. AD is highly heritable, with heritability estimates of ∼70% from twin studies. Progressively larger genome-wide association studies (GWAS) have continued to expand o...

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Detalles Bibliográficos
Autores principales:	Andrews, Shea J., Renton, Alan E., Fulton-Howard, Brian, Podlesny-Drabiniok, Anna, Marcora, Edoardo, Goate, Alison M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024184/ https://www.ncbi.nlm.nih.gov/pubmed/36907103 http://dx.doi.org/10.1016/j.ebiom.2023.104511

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