Prostaglandin E(2) Production by Brain Endothelial Cells and the Generation of Fever

We recently demonstrated that prostaglandin production in brain endothelial cells is both necessary and sufficient for the generation of fever during systemic immune challenge. I here discuss this finding in light of the previous literature and point to some unresolved issues.

Detalles Bibliográficos
Autor principal: Blomqvist, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2023
Materias:
DNACB Bit
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024267/
https://www.ncbi.nlm.nih.gov/pubmed/36720071
http://dx.doi.org/10.1089/dna.2022.0662
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author Blomqvist, Anders
author_facet Blomqvist, Anders
author_sort Blomqvist, Anders
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description We recently demonstrated that prostaglandin production in brain endothelial cells is both necessary and sufficient for the generation of fever during systemic immune challenge. I here discuss this finding in light of the previous literature and point to some unresolved issues.
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spelling pubmed-100242672023-03-19 Prostaglandin E(2) Production by Brain Endothelial Cells and the Generation of Fever Blomqvist, Anders DNA Cell Biol DNACB Bit We recently demonstrated that prostaglandin production in brain endothelial cells is both necessary and sufficient for the generation of fever during systemic immune challenge. I here discuss this finding in light of the previous literature and point to some unresolved issues. Mary Ann Liebert, Inc., publishers 2023-03-01 2023-03-13 /pmc/articles/PMC10024267/ /pubmed/36720071 http://dx.doi.org/10.1089/dna.2022.0662 Text en © Anders Blomqvist 2023; Published by Mary Ann Liebert, Inc. https://creativecommons.org/licenses/by/4.0/This Open Access article is distributed under the terms of the Creative Commons License [CC-BY] (http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle DNACB Bit
Blomqvist, Anders
Prostaglandin E(2) Production by Brain Endothelial Cells and the Generation of Fever
title Prostaglandin E(2) Production by Brain Endothelial Cells and the Generation of Fever
title_full Prostaglandin E(2) Production by Brain Endothelial Cells and the Generation of Fever
title_fullStr Prostaglandin E(2) Production by Brain Endothelial Cells and the Generation of Fever
title_full_unstemmed Prostaglandin E(2) Production by Brain Endothelial Cells and the Generation of Fever
title_short Prostaglandin E(2) Production by Brain Endothelial Cells and the Generation of Fever
title_sort prostaglandin e(2) production by brain endothelial cells and the generation of fever
topic DNACB Bit
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024267/
https://www.ncbi.nlm.nih.gov/pubmed/36720071
http://dx.doi.org/10.1089/dna.2022.0662
work_keys_str_mv AT blomqvistanders prostaglandine2productionbybrainendothelialcellsandthegenerationoffever

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